Atypical Teratoid/Rhabdoid tumor: Cytology and differential diagnosis in adults

被引:20
作者
Raisanen, J
Hatanpaa, KJ
Mickey, BE
White, CL
机构
[1] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Dept Neurol Surg, Dallas, TX 75390 USA
关键词
brain; tumor; rhabdoid; cytoloay;
D O I
10.1002/dc.20064
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Atypical teratoid/rhabdoid tumors (AT/RTs) are malignant intracranial neoplasms that usually occur in the posterior fossa of children. They are characterized by cells with paranuclear rhabdoid inclusions, a mesenchymal and epithelial immunohistochemical profile, and 22q deletions with inactivation of the IN11/hSNF5 gene. Although they usually occur in young children, AT/RTs are being recognized in adults with increasing frequency. We report the cytologic features of an AT/RT from the cerebellum of a 45-year-old man and discuss the differential diagnosis in adults. (C) 2004 Wiley-Liss. Inc.
引用
收藏
页码:60 / 63
页数:4
相关论文
共 21 条
[1]   Primary malignant rhabdoid tumour of the brain in an adult [J].
Arrazola, J ;
Pedrosa, I ;
Méndez, R ;
Saldaña, C ;
Scheithauer, BW ;
Martínez, A .
NEURORADIOLOGY, 2000, 42 (05) :363-367
[2]  
Ashraf R, 1997, MED PEDIATR ONCOL, V28, P223, DOI 10.1002/(SICI)1096-911X(199703)28:3<223::AID-MPO14>3.0.CO
[3]  
2-F
[4]  
Ben Taib NO, 1999, NEUROCHIRURGIE, V45, P237
[5]   A role for fluorescence in situ hybridization detection of chromosome 22q dosage in distinguishing atypical teratoid/rhabdoid tumors from medulloblastoma/central primitive neuroectodermal tumors [J].
Bruch, LA ;
Hill, DA ;
Cai, DX ;
Levy, BK ;
Dehner, LP ;
Perry, A .
HUMAN PATHOLOGY, 2001, 32 (02) :156-162
[6]  
Byram D, 1999, INT J RADIAT ONCOL, V45, P247
[7]   RHABDOID TUMORS OF THE CENTRAL-NERVOUS-SYSTEM - REPORT OF 3 CASES WITH IMMUNOCYTOCHEMICAL AND ULTRASTRUCTURAL FINDINGS [J].
COSSU, A ;
MASSARELLI, G ;
MANETTO, V ;
VIALE, G ;
TANDA, F ;
BOSINCU, L ;
IUZZOLINO, P ;
COSSU, S ;
PADOVANI, R ;
EUSEBI, V .
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1993, 422 (01) :81-85
[8]   Malignant rhabdoid tumor of brain: An aggressive clinical entity [J].
Fisher, BJ ;
Siddiqui, J ;
MacDonald, D ;
Cairney, AE ;
Ramsey, D ;
Munoz, D ;
DelMaestro, R .
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1996, 23 (04) :257-263
[9]   Chromosome 22q dosage in composite extrarenal rhabdoid tumors: Clonal evolution or a phenotypic mimic? [J].
Fuller, CE ;
Pfeifer, J ;
Humphrey, P ;
Bruch, LA ;
Dehner, LP ;
Perry, A .
HUMAN PATHOLOGY, 2001, 32 (10) :1102-1108
[10]  
Gessl M, 2003, BRAIN PATHOL, V13, P409