Synthesis and self-assembly behavior of a biodegradable and sustainable soybean oil-based copolymer nanomicelle

被引：22

作者：

Bao, Lixia ^{[1
,2
]}

Bian, Longchun ^{[2
]}

Zhao, Mimi ^{[2
]}

Lei, Jingxin ^{[1
]}

Wang, Jiliang ^{[2
]}

机构：

[1] Sichuan Univ, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China

[2] Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Peoples R China

来源：

NANOSCALE RESEARCH LETTERS | 2014年 / 9卷

基金：

中国国家自然科学基金;

关键词：

Soybean oil; Self-assembly; Nanomicelle; Biomaterials; TISSUE; POLYMERS; SCAFFOLD; FABRICATION; DELIVERY; DESIGN;

D O I：

10.1186/1556-276X-9-391

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Herein, we report a novel amphiphilic biodegradable and sustainable soybean oil-based copolymer (SBC) prepared by grafting hydrophilic and biocompatible hydroxyethyl acrylate (HEA) polymeric segments onto the natural hydrophobic soybean oil chains. FTIR, H-1-NMR, and GPC measurements have been used to investigate the molecular structure of the obtained SBC macromolecules. Self-assembly behaviors of the prepared SBC in aqueous solution have also been extensively evaluated by fluorescence spectroscopy and transmission electron microscopy. The prepared SBC nanocarrier with the size range of 40 to 80 nm has a potential application in the biomedical field.

引用

页码：1 / 6

页数：6

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