Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging

被引：15
作者：
Ncapayi, Vuyelwa [1 ,2 ]
Parani, Sundararajan [1 ,2 ]
Songca, Sandile P. [3 ]
Kodama, Tetsuya [4 ]
Oluwafemi, Oluwatobi S. [1 ,2 ]
机构：
[1] Univ Johannesburg, Dept Appl Chem, Doornfontein Campus,POB 17011, ZA-2028 Johannesburg, South Africa
[2] Univ Johannesburg, Ctr Nanomat Sci Res, Johannesburg, South Africa
[3] Univ Zululand, Dept Chem, Private Bag X1001, ZA-3886 Kwa Dlangezwa, South Africa
[4] Tohoku Univ, Grad Sch Biomed Engn, Aoba Ku, 4-1 Seiryo, Sendai, Miyagi 9808575, Japan
来源：
MATERIALS LETTERS | 2017年 / 189卷
基金：
新加坡国家研究基金会;
关键词：
CdTe/CdSe/ZnSe; Nanoparticles; KM-Luc/GFP cell; arginine; Functionalisation; QUANTUM DOTS; NANOCRYSTALS; NANOPARTICLES;
D O I：
10.1016/j.matlet.2016.12.006
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV-vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：168 / 171
页数：4
相关论文
共 18 条
  • [1] Quantum dot bioconjugates for ultrasensitive nonisotopic detection
    Chan, WCW
    Nie, SM
    [J]. SCIENCE, 1998, 281 (5385) : 2016 - 2018
  • [2] Microwave-Assisted Synthesis of Glutathione-Capped CdTe/CdSe Near-Infrared Quantum Dots for Cell Imaging
    Chen, Xiaogang
    Li, Liang
    Lai, Yongxian
    Yan, Jianna
    Tang, Yichen
    Wang, Xiuli
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (05) : 11500 - 11508
  • [3] Electroluminescence from single monolayers of nanocrystals in molecular organic devices
    Coe, S
    Woo, WK
    Bawendi, M
    Bulovic, V
    [J]. NATURE, 2002, 420 (6917) : 800 - 803
  • [4] In vivo imaging of quantum dots encapsulated in phospholipid micelles
    Dubertret, B
    Skourides, P
    Norris, DJ
    Noireaux, V
    Brivanlou, AH
    Libchaber, A
    [J]. SCIENCE, 2002, 298 (5599) : 1759 - 1762
  • [5] Preparation and study of colloid-chemical and optical properties of the nanocrystals of zinc sulfide modified with amino acids
    Erlikh, G. V.
    Shcherba, T. N.
    Zhilenko, M. P.
    Murav'eva, G. P.
    Lisichkin, G. V.
    [J]. RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2010, 80 (06) : 1109 - 1114
  • [6] Simple synthesis of amino acid-functionalized hydrophilic upconversion nanoparticles capped with both carboxyl and amino groups for bimodal imaging
    Han, Gui-Mei
    Jiang, Hong-Xin
    Huo, Yan-Fang
    Kong, De-Ming
    [J]. JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4 (19) : 3351 - 3357
  • [7] Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification
    Hoshino, A
    Fujioka, K
    Oku, T
    Suga, M
    Sasaki, YF
    Ohta, T
    Yasuhara, M
    Suzuki, K
    Yamamoto, K
    [J]. NANO LETTERS, 2004, 4 (11) : 2163 - 2169
  • [8] Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles
    Kirchner, C
    Liedl, T
    Kudera, S
    Pellegrino, T
    Javier, AM
    Gaub, HE
    Stölzle, S
    Fertig, N
    Parak, WJ
    [J]. NANO LETTERS, 2005, 5 (02) : 331 - 338
  • [9] Klostranec J.M., 1953, ADV MAT, V18
  • [10] Mei-Xia Z., 2011, CHEM-EUR J, V17, P5171
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