Sodium carbonate as a solid-phase reagent for the generation of acetylketene

被引：9

作者：

Bell, Kelcey ^{[1
]}

Sadasivam, Dhandapani V. ^{[1
]}

Gudipati, Indra Reddy ^{[1
]}

Ji, Hua ^{[1
]}

Birney, David ^{[1
]}

机构：

[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 12期

基金：

美国国家科学基金会;

关键词：

ASYMMETRIC CATALYSIS;

D O I：

10.1016/j.tetlet.2009.01.008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of a toluene solution of 3-oxobutanoyl chloride (14) with Na2CO3 in the presence of a catalytic amount of triethylamine at 78 degrees C generates a solution of acetylketene (2), the dimer of which was isolated. Acetylketene (2) was trapped with 2-propanone, 2-propanol, and ethyl vinyl ether. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1295 / 1297

页数：3

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