Digital Light Processing Bioprinting Advances for Microtissue Models

被引：72

作者：

Hosseinabadi, Hossein Goodarzi ^{[1
]}

Dogan, Elvan ^{[2
]}

Miri, Amir K. ^{[2
,3
]}

Ionov, Leonid ^{[1
,4
]}

机构：

[1] Univ Bayreuth, Fac Engn Sci, Dept Biofabricat, D-95447 Bayreuth, Germany

[2] New Jersey Inst Technol, Dept Biomed Engn, Newark, NJ 07102 USA

[3] New Jersey Inst Technol, Dept Mech & Ind Engn, Newark, NJ 07102 USA

[4] Univ Bayreuth, Bavarian Polymer Inst, Dept Biofabricat, D-95447 Bayreuth, Germany

来源：

ACS BIOMATERIALS SCIENCE & ENGINEERING | 2022年 / 8卷 / 04期

关键词：

digital light processing; tissue engineering; bioprinter design; vascularized models; TUMOR-CELL; 3D; STEREOLITHOGRAPHY; FABRICATION; HYDROGELS; PHOTOPOLYMERIZATION; MICROSTRUCTURES; TECHNOLOGIES; NETWORKS;

D O I：

10.1021/acsbiomaterials.1c01509

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Digital light processing (DLP) bioprinting has been widely introduced as a fastand robust biofabrication method in tissue engineering. The technique holds a great promisefor creating tissue models because it can replicate the resolution and complexity of naturaltissues and constructs. A DLP system projects 2D images onto layers of bioink using a digitalphotomask. The resolution of DLP bioprinting strongly depends on the characteristics of theprojected light and the photo-cross-linking response of the bioink microenvironment. In thisreview, we present a summary of DLP fundamentals with a focus on bioink properties,photoinitiator selection, and light characteristics in resolution of bioprinted constructs. Asimple guideline is provided for bioengineers interested in using DLP platforms andcustomizing technical specifications for its design. The literature review reveals the promisingfuture of DLP bioprinting for disease modeling and biofabrication

引用

页码：1381 / 1395

页数：15

共 90 条

[1] Stereolithography of spatially controlled multi-material bioactive poly(ethylene glycol) scaffolds [J].

Arcaute, Karina ;

Mann, Brenda ;

Wicker, Ryan .

ACTA BIOMATERIALIA, 2010, 6 (03) :1047-1054

[2] Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients [J].

Baker, Brendon M. ;

Trappmann, Britta ;

Stapleton, Sarah C. ;

Toro, Esteban ;

Chen, Christopher S. .

LAB ON A CHIP, 2013, 13 (16) :3246-3252

[3] Engineered In Vitro Disease Models [J].

Benam, Kambez H. ;

Dauth, Stephanie ;

Hassell, Bryan ;

Herland, Anna ;

Jain, Abhishek ;

Jang, Kyung-Jin ;

Karalis, Katia ;

Kim, Hyun Jung ;

MacQueen, Luke ;

Mahmoodian, Roza ;

Musah, Samira ;

Torisawa, Yu-suke ;

van der Meer, Andries D. ;

Villenave, Remi ;

Yadid, Moran ;

Parker, Kevin K. ;

Ingber, Donald E. .

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10, 2015, 10 :195-262

[4] 3D functional and perfusable microvascular networks for organotypic microfluidic models [J].

Bersini, Simone ;

Moretti, Matteo .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2015, 26 (05)

[5] Microfluidic organs-on-chips [J].

Bhatia, Sangeeta N. ;

Ingber, Donald E. .

NATURE BIOTECHNOLOGY, 2014, 32 (08) :760-772

[6] Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips [J].

Bhusal, Anant ;

Dogan, Elvan ;

Nguyen, Hai-Anh ;

Labutina, Olga ;

Nieto, Daniel ;

Khademhosseini, Ali ;

Miri, Amir K. .

BIOFABRICATION, 2022, 14 (01)

[7] Microfluidic model of ductal carcinoma in situ with 3D, organotypic structure [J].

Bischel, Lauren L. ;

Beebe, David J. ;

Sung, Kyung E. .

BMC CANCER, 2015, 15

[8] 3D bioprinting of cell-laden hydrogels for advanced tissue engineering [J].

Blaeser, Andreas ;

Campos, Daniela Filipa Duarte ;

Fischer, Horst .

CURRENT OPINION IN BIOMEDICAL ENGINEERING, 2017, 2 :58-66

[9] Multi-Organs-on-Chips for Testing Small-Molecule Drugs: Challenges and Perspectives [J].

Cecen, Berivan ;

Karavasili, Christina ;

Nazir, Mubashir ;

Bhusal, Anant ;

Dogan, Elvan ;

Shahriyari, Fatemeh ;

Tamburaci, Sedef ;

Buyukoz, Melda ;

Kozaci, Leyla Didem ;

Miri, Amir K. .

PHARMACEUTICS, 2021, 13 (10)

[10] Three-dimensional photopatterning of hydrogels using stereolithography for long-term cell encapsulation [J].

Chan, Vincent ;

Zorlutuna, Pinar ;

Jeong, Jae Hyun ;

Kong, Hyunjoon ;

Bashir, Rashid .

LAB ON A CHIP, 2010, 10 (16) :2062-2070

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