Imidazolium Salt Catalyzed para-Selective Halogenation of Electron-Rich Arenes

被引：18

作者：

Chen, Jie ^{[1
,2
]}

Xiong, Xiaoyu ^{[1
,2
]}

Chen, Zenghua ^{[1
,2
]}

Huang, Jianhui ^{[1
,2
]}

机构：

[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Delivery & High Effic, Tianjin 300072, Peoples R China

[2] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China

来源：

SYNLETT | 2015年 / 26卷 / 20期

基金：

中国国家自然科学基金;

关键词：

arenes; regioselectivity; halogenation; amides; ethers; catalysis; CROSS-COUPLING REACTIONS; C-H; BROMINATION; MILD; CHLORINATION; ARYLAMINES; ACTIVATION; VERSATILE;

D O I：

10.1055/s-0035-1560376

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly para-selective halogenation of arenes bearing coordinating groups in the presence of a dimidazolium salt as a catalyst is reported. A series of electron-rich p-haloarenes were prepared in good yields and good to excellent selectivities. We also propose a plausible mechanism for the catalytic reaction.

引用

页码：2831 / 2834

页数：4

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