Sonolithography: In-Air Ultrasonic Particulate and Droplet Manipulation for Multiscale Surface Patterning

被引:11
|
作者
Shapiro, Jenna M. [1 ]
Drinkwater, Bruce W. [1 ]
Perriman, Adam W. [2 ]
Fraser, Mike [3 ]
机构
[1] Univ Bristol, Fac Engn, Bristol BS8 1TR, Avon, England
[2] Univ Bristol, Sch Cellular & Mol Med, Bristol BS8 1TD, Avon, England
[3] Univ Bath, Dept Comp Sci, Bath BA2 7AY, Avon, England
基金
英国工程与自然科学研究理事会;
关键词
acoustic patterning; acoustophoresis; biofabrication; surface patterning; ultrasound; ACOUSTIC RADIATION FORCE; CELL; FIELD; PARTICLE; TRANSDUCERS; FABRICATION; AEROSOL;
D O I
10.1002/admt.202000689
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Acoustic fields are increasingly being used in material handling applications for gentle, noncontact manipulation of particles in fluids. Sonolithography is based on the application of acoustic radiation forces arising from the interference of ultrasonic standing waves to direct airborne particle/droplet accumulation in defined spatial regions. This approach enables reliable and repeatable patterning of materials onto a substrate to provide spatially localized topographical or biochemical cues, structural features, or other functionalities that are relevant to biofabrication and tissue engineering applications. The technique capitalizes on inexpensive, commercially available transducers and electronics. Sonolithography is capable of rapidly patterning micrometer to millimeter scale materials onto a wide variety of substrates over a macroscale (cm(2)) surface area and can be used for both indirect and direct cell patterning.
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页数:8
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