Prediction of Mortality and Postoperative Complications using the Hip-Multidimensional Frailty Score in Elderly Patients with Hip Fracture

被引:50
作者
Choi, Jung-Yeon [1 ]
Cho, Kwan-Jae [2 ]
Kim, Sun-wook [1 ,3 ]
Yoon, Sol-Ji [1 ]
Kang, Min-gu [1 ]
Kim, Kwang-il [1 ,3 ]
Lee, Young-Kyun [4 ]
Koo, Kyung-Hoi [2 ,4 ]
Kim, Cheol-Ho [1 ,3 ]
机构
[1] Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea
[2] Seoul Natl Univ, Dept Orthoped Surg, Coll Med, Seoul, South Korea
[3] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Dept Orthoped Surg, Seongnam, South Korea
关键词
GAIT SPEED; INSTITUTIONALIZATION; MORBIDITY; SURGERY; RISK; SURVIVAL; OUTCOMES; QUALITY; PEOPLE; WOMEN;
D O I
10.1038/srep42966
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (>= 65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcome was the 6-month all-cause mortality rate. The secondary outcomes were 1-year all-cause mortality, postoperative complications and prolonged hospital stay, and institutionalization. Thirty-five patients (7.3%) died within 6 months after surgery (median [interquartile range], 2.9 [1.4-3.9] months). The fully adjusted hazard ratio per 1 point increase in Hip-MFS was 1.458 (95% confidence interval [CI]: 1.210-1.758) for 6-months mortality and odds ratio were 1.239 (95% CI: 1.115-1.377), 1.156 (95% CI: 1.031-1.296) for postoperative complications and prolonged total hospital stay, respectively. High-risk patients (Hip-MFS > 8) showed higher risk of 6-month mortality (hazard ratio: 3.545, 95% CI: 1.466-8.572) than low-risk patients after adjustment. Hip-MFS successfully predict 6-month mortality, postoperative complications and prolonged hospital stay in elderly hip fracture patients after surgery. Hip-MFS more precisely predict 6-month mortality than age or existing tools (P values of comparison of ROC curve: 0.002, 0.004, and 0.044 for the ASA classification, age and NHFS, respectively).
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页数:8
相关论文
共 34 条
[21]   Five-Year Relative Survival of Patients With Osteoporotic Hip Fracture [J].
Lee, Young-Kyun ;
Lee, You-Jin ;
Ha, Yong-Chan ;
Koo, Kyung-Hoi .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (01) :97-100
[22]   Frailty as a Predictor of Surgical Outcomes in Older Patients [J].
Makary, Martin A. ;
Segev, Dorry L. ;
Pronovost, Peter J. ;
Syin, Dora ;
Bandeen-Roche, Karen ;
Patel, Purvi ;
Takenaga, Ryan ;
Devgan, Lara ;
Holzmueller, Christine G. ;
Tian, Jing ;
Fried, Linda P. .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2010, 210 (06) :901-908
[23]   PREDICTORS OF MORTALITY AND INSTITUTIONALIZATION AFTER HIP FRACTURE - THE NEW-HAVEN EPESE COHORT [J].
MAROTTOLI, RA ;
BERKMAN, LF ;
LEOSUMMERS, L ;
COONEY, LM .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1994, 84 (11) :1807-1812
[24]   Development and validation of a preoperative scoring system to predict 30 day mortality in patients undergoing hip fracture surgery [J].
Maxwell, M. J. ;
Moran, C. G. ;
Moppett, I. K. .
BRITISH JOURNAL OF ANAESTHESIA, 2008, 101 (04) :511-517
[25]   The association of race, gender, and comorbidity with mortality and function after hip fracture [J].
Penrod, Joan D. ;
Litke, Ann ;
Hawkes, William G. ;
Magaziner, Jay ;
Doucette, John T. ;
Koval, Kenneth J. ;
Silberzweig, Stacey B. ;
Egol, Kenneth A. ;
Siu, Albert L. .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2008, 63 (08) :867-872
[26]   Redefining Geriatric Preoperative Assessment Using Frailty, Disability and Co-Morbidity [J].
Robinson, Thomas N. ;
Eiseman, Ben ;
Wallace, Jeffrey I. ;
Church, Skotti D. ;
McFann, Kim K. ;
Pfister, Shirley M. ;
Sharp, Terra J. ;
Moss, Marc .
ANNALS OF SURGERY, 2009, 250 (03) :449-455
[27]  
Roche J J W, 2005, BMJ, V331, P1374
[28]   Preoperative Frailty and Quality of Life as Predictors of Postoperative Complications [J].
Saxton, Adrienne ;
Velanovich, Vic .
ANNALS OF SURGERY, 2011, 253 (06) :1223-1229
[29]   Pre-operative indicators for mortality following hip fracture surgery: a systematic review and meta-analysis [J].
Smith, Toby ;
Pelpola, Kelum ;
Ball, Martin ;
Ong, Alice ;
Myint, Phyo Kyaw .
AGE AND AGEING, 2014, 43 (04) :464-471
[30]   Gait Speed and Survival in Older Adults [J].
Studenski, Stephanie ;
Perera, Subashan ;
Patel, Kushang ;
Rosano, Caterina ;
Faulkner, Kimberly ;
Inzitari, Marco ;
Brach, Jennifer ;
Chandler, Julie ;
Cawthon, Peggy ;
Connor, Elizabeth Barrett ;
Nevitt, Michael ;
Visser, Marjolein ;
Kritchevsky, Stephen ;
Badinelli, Stefania ;
Harris, Tamara ;
Newman, Anne B. ;
Cauley, Jane ;
Ferrucci, Luigi ;
Guralnik, Jack .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (01) :50-58