Prediction of Mortality and Postoperative Complications using the Hip-Multidimensional Frailty Score in Elderly Patients with Hip Fracture

被引:50
作者
Choi, Jung-Yeon [1 ]
Cho, Kwan-Jae [2 ]
Kim, Sun-wook [1 ,3 ]
Yoon, Sol-Ji [1 ]
Kang, Min-gu [1 ]
Kim, Kwang-il [1 ,3 ]
Lee, Young-Kyun [4 ]
Koo, Kyung-Hoi [2 ,4 ]
Kim, Cheol-Ho [1 ,3 ]
机构
[1] Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea
[2] Seoul Natl Univ, Dept Orthoped Surg, Coll Med, Seoul, South Korea
[3] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Seongnam, South Korea
[4] Seoul Natl Univ, Bundang Hosp, Dept Orthoped Surg, Seongnam, South Korea
关键词
GAIT SPEED; INSTITUTIONALIZATION; MORBIDITY; SURGERY; RISK; SURVIVAL; OUTCOMES; QUALITY; PEOPLE; WOMEN;
D O I
10.1038/srep42966
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
High mortality and dependent living after hip fracture pose a significant public health concern. Retrospective study was conducted with 481 hip fracture patients (>= 65 years of age) undergoing surgery from March 2009 to May 2014. The Hip-MFS was calculated by Comprehensive Geriatric Assessment (CGA). The primary outcome was the 6-month all-cause mortality rate. The secondary outcomes were 1-year all-cause mortality, postoperative complications and prolonged hospital stay, and institutionalization. Thirty-five patients (7.3%) died within 6 months after surgery (median [interquartile range], 2.9 [1.4-3.9] months). The fully adjusted hazard ratio per 1 point increase in Hip-MFS was 1.458 (95% confidence interval [CI]: 1.210-1.758) for 6-months mortality and odds ratio were 1.239 (95% CI: 1.115-1.377), 1.156 (95% CI: 1.031-1.296) for postoperative complications and prolonged total hospital stay, respectively. High-risk patients (Hip-MFS > 8) showed higher risk of 6-month mortality (hazard ratio: 3.545, 95% CI: 1.466-8.572) than low-risk patients after adjustment. Hip-MFS successfully predict 6-month mortality, postoperative complications and prolonged hospital stay in elderly hip fracture patients after surgery. Hip-MFS more precisely predict 6-month mortality than age or existing tools (P values of comparison of ROC curve: 0.002, 0.004, and 0.044 for the ASA classification, age and NHFS, respectively).
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页数:8
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