A Comparison Among the Models Proposed to Explain the Origin of the tRNA Molecule: A Synthesis

被引:52
作者
Di Giulio, Massimo [1 ]
机构
[1] CNR, Lab Mol Evolut, Inst Genet & Biophys, I-80131 Naples, Italy
关键词
Corroboration/falsification of theories; Transition stages; Molecular fossils of genes; Ancestral stages; Missing link; Hairpin Structure; NON-MONOPHYLETIC ORIGIN; GENETIC-CODE; PROTEIN-SYNTHESIS; CYANIDIOSCHYZON-MEROLAE; NANOARCHAEUM-EQUITANS; RIBOSOMAL-RNAS; ACCEPTOR STEM; CIRCULAR RNA; AMINO-ACIDS; HAIRPIN RNA;
D O I
10.1007/s00239-009-9248-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A comparison is made among all the models proposed to explain the origin of the tRNA molecule. The conclusion reached is that, for the model predicting that the tRNA molecule originated after the assembly of two hairpin-like structures, molecular fossils have been found in the half-enes of the tRNAs of Nanoarchaeum equitans. These might be the witnesses of the transition stage predicted by the model through which the evolution of the tRNA molecule passed, thus providing considerable corroboration for this model.
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页码:1 / 9
页数:9
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