Air pollution: A culprit of lung cancer

被引：114

作者：

Xue, Yueguang ^{[1
,2
,3
,4
]}

Wang, Liuxiang ^{[1
,2
,3
,4
]}

Zhang, Yiming ^{[2
,3
,4
]}

Zhao, Yuliang ^{[2
,3
,5
]}

Liu, Ying ^{[1
,2
,3
,5
]}

机构：

[1] Zhengzhou Univ, Sch Basic Med Sci, Zhengzhou 450001, Peoples R China

[2] Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nano Safety, Beijing 100190, Peoples R China

[3] Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China

[4] Zhengzhou Univ, Henan Inst Adv Technol, Zhengzhou 450052, Peoples R China

[5] GBA Natl Inst Nanotechnol Innovat, Guangzhou 510700, Guangdong, Peoples R China

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2022年 / 434卷

基金：

中国国家自然科学基金;

关键词：

Air pollution; Lung cancer; Health; Pathogenesis; FINE PARTICULATE MATTER; LONG-TERM EXPOSURE; NONTYPABLE HAEMOPHILUS-INFLUENZAE; OXIDATIVE STRESS; PERSONAL EXPOSURE; DIFFERENT SIZES; RISK-ASSESSMENT; NEVER-SMOKERS; CELL-CYCLE; DNA-DAMAGE;

D O I：

10.1016/j.jhazmat.2022.128937

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Air pollution is a global health problem, especially in the context of rapid economic development and the expansion of urbanization. Herein, we discuss the harmful effects of outdoor and indoor pollution on the lungs. Ambient particulate matters (PMs) from industrial and vehicle exhausts is associated with lung cancer. Workers exposed to asbestos, polycyclic aromatic hydrocarbons (PAHs), and toxic metals are also likely to develop lung cancer. Indoors, cooking fumes, second-hand smoke, and radioactive products from house decoration materials play roles in the development of lung cancer. Bacteria and viruses can also be detrimental to health and are important risk factors in lung inflammation and cancer. Specific effects of lung cancer caused by air pollution are discussed in detail, including inflammation, DNA damage, and epigenetic regulation. In addition, advanced materials for personal protection, as well as the current government policies to prevent air pollution, are summarized. This review provides a basis for future research on the relationship between lung cancer and air pollution.

引用

页数：15