Microwave-assisted synthesis of novel fluorinated 1,2,4-triazole derivatives, and study of their biological activity

被引:70
作者
Liu, Xing-Hai [1 ]
Weng, Jian-Quan [1 ]
Wang, Bao-Lei [2 ]
Li, Yong-Hong [2 ]
Tan, Cheng-Xia [1 ]
Li, Zheng-Ming [2 ]
机构
[1] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China
[2] Nankai Univ, Natl Pesticidal Engn Ctr, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
基金
中国国家自然科学基金;
关键词
1,2,4-Triazole; Fluorine; Herbicidal activity; Microwave irradiation synthesis; FUNGICIDAL ACTIVITY; CRYSTAL-STRUCTURE; CYCLOPROPANE MOIETY; 1,2,3-THIADIAZOLE; BIOACTIVITY;
D O I
10.1007/s11164-013-1113-4
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Microwave irradiation was used for synthesis of a series of novel fluorinated 1,2,4-triazole derivatives. The molecular structures of the compounds were determined by use of H-1 NMR and FTIR spectroscopy and MS and HRMS. Study of their biological activity showed most of the compounds had good herbicidal activity.
引用
收藏
页码:2605 / 2612
页数:8
相关论文
共 18 条
[1]   Microwave-assisted Synthesis and Bioevaluation of Some Semicarbazones [J].
Jafri, Laila ;
Ansari, Farzana L. ;
Jamil, Maryam ;
Kalsoom, Saima ;
Qureishi, Sana ;
Mirza, Bushra .
CHEMICAL BIOLOGY & DRUG DESIGN, 2012, 79 (06) :950-959
[2]   Synthesis and fungicidal activity of new fluorine-containing mandelic acid amide compounds [J].
Li, Shuai ;
Cui, Can ;
Wang, Man-Yi ;
Yu, Shui-Jing ;
Shi, Yan-Xia ;
Zhang, Xiao ;
Li, Zheng-Ming ;
Zhao, Wei-Guang ;
Li, Bao-Ju .
JOURNAL OF FLUORINE CHEMISTRY, 2012, 137 :108-112
[3]   Synthesis, bioactivity and DFT structure-activity relationship study of novel 1,2,3-thiadiazole derivatives [J].
Liu, Xing-Hai ;
Zhao, Wei-Guang ;
Wang, Bao-Lei ;
Li, Zheng-Ming .
RESEARCH ON CHEMICAL INTERMEDIATES, 2012, 38 (08) :1999-2008
[4]   Synthesis, structure, and biological activity of novel (oxdi/tri)azoles derivatives containing 1,2,3-thiadiazole or methyl moiety [J].
Liu, Xing-Hai ;
Pan, Li ;
Weng, Jian-Quan ;
Tan, Cheng-Xia ;
Li, Yong-Hong ;
Wang, Bao-Lei ;
Li, Zheng-Ming .
MOLECULAR DIVERSITY, 2012, 16 (02) :251-260
[5]   Synthesis, crystal structure, bioactivity and DFT calculation of new oxime ester derivatives containing cyclopropane moiety [J].
Liu, Xing-Hai ;
Pan, Li ;
Tan, Cheng-Xia ;
Weng, Jian-Quan ;
Wang, Bao-Lei ;
Li, Zheng-Ming .
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2011, 101 (03) :143-147
[6]   Design, Synthesis, Biological Activities, and 3D-QSAR of New N,N′-Diacylhydrazines Containing 2-(2,4-dichlorophenoxy)propane Moiety [J].
Liu, Xing-Hai ;
Pan, Li ;
Ma, Yi ;
Weng, Jian-Quan ;
Tan, Cheng-Xia ;
Li, Yong-Hong ;
Shi, Yan-Xia ;
Li, Bao-Ju ;
Li, Zheng-Ming ;
Zhang, Yong-Gang .
CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 78 (04) :689-694
[7]  
Liu XH, 2011, ASIAN J CHEM, V23, P4064
[8]   SYNTHESIS, DIMERIC CRYSTAL STRUCTURE, AND FUNGICIDAL ACTIVITY OF 1-(4-METHYLPHENYL)-2-(5-((3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHYL)-4-PHENYL-4H-1,2,4-TRIAZOL-3-YLTHIO)ETHANONE [J].
Liu, Xing-Hai ;
Tan, Cheng-Xia ;
Weng, Jian-Quan .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2011, 186 (03) :558-564
[9]   PHASE TRANSFER-CATALYZED, ONE-POT SYNTHESIS OF SOME NOVEL N-PYRIMIDINYL-N′-NICOTINYL THIOUREA DERIVATIVES [J].
Liu, Xing-Hai ;
Tan, Cheng-Xia ;
Weng, Jian-Quan .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2011, 186 (03) :552-557
[10]   Synthesis, bioactivity, theoretical and molecular docking study of 1-cyano-N-substituted-cyclopropanecarboxamide as ketol-acid reductoisomerase inhibitor [J].
Liu, Xing-Hal ;
Chen, Pei-Quan ;
Wang, Bao-Lei ;
Li, Yong-Hong ;
Wang, Su-Hua ;
Li, Zheng-Ming .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (13) :3784-3788