Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO

被引:29
作者
Broome, Michael [1 ,2 ,3 ]
Donker, Dirk W. [4 ]
机构
[1] KTH Royal Inst Technol, Sch Technol & Hlth, S-14152 Stockholm, Sweden
[2] Karolinska Univ Hosp, Astrid Lindgren Childrens Hosp, ECMO Ctr, S-17176 Stockholm, Sweden
[3] Karolinska Inst, Dept Physiol & Pharmacol, Anesthesiol & Intens Care Med, S-17177 Stockholm, Sweden
[4] Univ Med Ctr Utrecht, Dept Intens Care Med, Utrecht, Netherlands
关键词
Extracorporeal life support (ECLS); Veno-arterial extracorporeal membrane oxygenation (ECMO); Realtime cardiovascular computer simulation; Cardiogenic shock; Heart failure; EXTRACORPOREAL LIFE-SUPPORT;
D O I
10.1186/s12967-015-0760-1
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.
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页数:5
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共 8 条
[1]   Acute lung injury after mechanical circulatory support implantation in patients on extracorporeal life support: an unrecognized problem† [J].
Boulate, David ;
Luyt, Charles-Edouard ;
Pozzi, Matteo ;
Niculescu, Michaela ;
Combes, Alain ;
Leprince, Pascal ;
Kirsch, Matthias .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2013, 44 (03) :544-549
[2]   Recirculation during veno-venous extra-corporeal membrane oxygenation - a simulation study [J].
Broman, Mikael ;
Frenckner, Bjorn ;
Bjallmark, Anna ;
Broome, Michael .
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 2015, 38 (01) :23-30
[3]   Closed-loop real-time simulation model of hemodynamics and oxygen transport in the cardiovascular system [J].
Broome, Michael ;
Maksuti, Elira ;
Bjallmark, Anna ;
Frenckner, Bjorn ;
Janerot-Sjoberg, Birgitta .
BIOMEDICAL ENGINEERING ONLINE, 2013, 12
[4]   Predictors of 30-day mortality and outcome in cases of myocardial infarction with cardiogenic shock treated by extracorporeal life support [J].
Demondion, Pierre ;
Fournel, Ludovic ;
Golmard, Jean-Louis ;
Niculescu, Michaela ;
Pavie, Alain ;
Leprince, Pascal .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2014, 45 (01) :47-54
[5]   Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging [J].
Lang, Roberto M. ;
Badano, Luigi P. ;
Mor-Avi, Victor ;
Afilalo, Jonathan ;
Armstrong, Anderson ;
Ernande, Laura ;
Flachskampf, Frank A. ;
Foster, Elyse ;
Goldstein, Steven A. ;
Kuznetsova, Tatiana ;
Lancellotti, Patrizio ;
Muraru, Denisa ;
Picard, Michael H. ;
Rietzschel, Ernst R. ;
Rudski, Lawrence ;
Spencer, Kirk T. ;
Tsang, Wendy ;
Voigt, Jens-Uwe .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2015, 28 (01) :1-U170
[6]   Outcomes, long-term quality of life, and psychologic assessment of fulminant myocarditis patients rescued by mechanical circulatory support [J].
Mirabel, Mariana ;
Luyt, Charles-Edouard ;
Leprince, Pascal ;
Trouillet, Jean-Louis ;
Leger, Philippe ;
Pavie, Alain ;
Chastre, Jean ;
Combes, Alain .
CRITICAL CARE MEDICINE, 2011, 39 (05) :1029-1035
[7]   Increasing venoarterial extracorporeal membrane oxygenation flow negatively affects left ventricular performance in a porcine model of cardiogenic shock [J].
Ostadal, Petr ;
Mlcek, Mikulas ;
Kruger, Andreas ;
Hala, Pavel ;
Lacko, Stanislav ;
Mates, Martin ;
Vondrakova, Dagmar ;
Svoboda, Tomas ;
Hrachovina, Matej ;
Janotka, Marek ;
Psotova, Hana ;
Strunina, Svitlana ;
Kittnar, Otomar ;
Neuzil, Petr .
JOURNAL OF TRANSLATIONAL MEDICINE, 2015, 13
[8]   Extracorporeal life support in cardiogenic shock: Impact of acute versus chronic etiology on outcome [J].
Tarzia, Vincenzo ;
Bortolussi, Giacomo ;
Bianco, Roberto ;
Buratto, Edward ;
Bejko, Jonida ;
Carrozzini, Massimiliano ;
De Franceschi, Marco ;
Gregori, Dario ;
Fichera, Dario ;
Zanella, Fabio ;
Bottio, Tomaso ;
Gerosa, Gino .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2015, 150 (02) :333-340