Effects of Low-Carbohydrate, High-Fat Diets on Body and Skeletal Muscle Weights in Mice

被引：0

作者：

Oshita, Kanako ^{[1
]}

Hara, Yurie ^{[2
]}

Watanabe, Nakamichi ^{[1
,3
]}

机构：

[1] Showa Womens Univ, Grad Sch Life Sci, Grad Program Life Sci & Design, Setagaya Ku, 1-7-57 Taishido, Tokyo 1548533, Japan

[2] Tamagawa Univ, Coll Agr, Dept Adv Food Sci, 6-1-1 Tamagawa Gakuen, Machida, Tokyo 1948610, Japan

[3] Showa Womens Univ, Inst Womens Hlth Sci, Setagaya Ku, 1-7-57 Taishido, Tokyo 1548533, Japan

来源：

JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 2020年 / 67卷 / 04期

关键词：

low-carbohydrate diet; skeletal muscle; body weight; mice; EXPRESSION; THERAPY;

D O I：

10.3136/nskkk.67.128

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Low-carbohydrate diets have anti-obesity effects induced by decreases in insulin secretion. Since insulin promotes the synthesis of proteins, the possibility that low-carbohydrate diets will decrease skeletal muscle weight is of concern. The purpose of this study was to examine whether low-carbohydrate, high-fat diets decrease skeletal muscle weight in mice. Ten-week-old male ICR mice were assigned to three groups (n=8 each) according to the energy proportion of carbohydrates in their diets as follows: Carb64 (protein:fat:carbohydrate =20:16:64), Carb32 (20:48:32), and Carb16 (20:64:16). The mice were dissected after four weeks. Low-carbohydrate, high-fat diets may decrease skeletal muscle weight by decreasing Myog expression, while the diets increased body weight.

引用

页码：128 / 133

页数：6

共 10 条

[1]

Evert AB, 2013, DIABETES CARE, V36, P3821, DOI [10.2337/dc13-2042, 10.2337/dc14-S120]

[2] A randomized trial of a low-carbohydrate diet for obesity [J].