Portulaca oleracea extracts protect human keratinocytes and fibroblasts from UV-induced apoptosis

被引：15
作者：
Lee, Suyeon [1 ]
Kim, Ki Ho [1 ]
Park, Changhoon [2 ]
Lee, Jong-Suk [2 ]
Kim, Young Heui [1 ]
机构：
[1] Bioland R&D Ctr, Cheonan 330863, Chungnam, South Korea
[2] AMOREPACIFIC Co R&D Ctr, Yongin, Gyeonggi Do, South Korea
来源：
EXPERIMENTAL DERMATOLOGY | 2014年 / 23卷
关键词：
apoptosis; fibroblast; keratinocyte; Portulaca oleracea extracts; UVB; ULTRAVIOLET-LIGHT; ANNEXIN-V; TELOMERES; MITOCHONDRIA; IRRADIATION; CANCER; CELLS;
D O I：
10.1111/exd.12396
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Portulaca oleracea extracts, known as Ma Chi Hyun in the traditional Korean medicine, show a variety of biomedical efficacies including those in anti-inflammation and anti-allergy. In this study, we investigate the protective activity of the P.oleracea extracts against UVB-induced damage in human epithelial keratinocytes and fibroblasts by several apoptosis-related tests. The results suggest that P.oleracea extracts have protective effects from UVB-induced apoptosis.
引用
收藏
页码：13 / 17
页数：5
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