Manganese(I)- Catalyzed C-H Aminocarbonylation of Heteroarenes

被引：109

作者：

Liu, Weiping ^{[1
]}

Bang, Jonas ^{[1
]}

Zhang, Yujiao ^{[1
]}

Ackermann, Lutz ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 47期

基金：

欧洲研究理事会;

关键词：

C-H activation; indoles; isocyanates; manganese; reaction mechanisms; BOND ACTIVATION; ISOCYANATES; AMIDATION; ARYLATIONS; OXIDATION; ARYL; FUNCTIONALIZATION; FLUORINATION; CYCLIZATION; ALKYLATION;

D O I：

10.1002/anie.201507087

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A versatile manganese(I) catalyst was employed in C-H aminocarbonylation reactions of heteroarenes with aryl as well as with alkyl isocyanates using a removable directing group approach. Detailed experimental mechanistic studies were suggestive of an organometallic C-H manganesation step, followed by a rate-determining migratory insertion.

引用

页码：14137 / 14140

页数：4

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