Carotid blowout syndrome after reirradiation for head and neck malignancies: a comprehensive systematic review for a pragmatic multidisciplinary approach

被引:24
作者
Alterio, Daniela [1 ]
Turturici, Irene [1 ]
Volpe, Stefania [1 ,2 ]
Ferrari, Annamaria [1 ]
Russell-Edu, Samuel William [3 ]
Vischioni, Barbara [4 ]
Mardighian, Dikran [5 ]
Preda, Lorenzo [6 ,7 ]
Gandini, Sara [8 ]
Marvaso, Giulia [1 ,2 ]
Augugliaro, Matteo [1 ]
Durante, Stefano [1 ]
Arculeo, Simona [1 ,2 ]
Patti, Filippo [1 ,2 ]
Boccuzzi, Dario [9 ]
Casbarra, Alessia [1 ,2 ]
Starzynska, Anna [10 ]
Santoni, Riccardo [11 ]
Jereczek-Fossa, Barbara Alicja [1 ,2 ]
机构
[1] European Inst Oncol IRCCS, Div Radiat Oncol, IEO, Milan, Italy
[2] Univ Milan, Dept Oncol & Hematooncol, Milan, Italy
[3] European Inst Oncol IRCCS, Lib, Milan, Italy
[4] Natl Ctr Oncol Hadrontherapy, Fdn CNAO, Pavia, Italy
[5] Spedali Civili Brescia, Neuroradiol Unit, Brescia, Italy
[6] Univ Pavia, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy
[7] Fdn IRCCS Policlin San Matteo Pavia, Dept Radiol, Pavia, Italy
[8] IEO European Inst Oncol IRCSS, Dept Expt Oncol, Milan, Italy
[9] Univ Pavia, Diagnost Radiol Residency Sch, Pavia, Italy
[10] Med Univ Gdansk, Dept Oral Surg, Gdansk, Poland
[11] Fdn Policlin Tor Vergata, Radiat Oncol Dept, Rome, Italy
关键词
Head and neck; Carotid blowout; Re-irradiation; Risk factors; Multidisciplinary management; STEREOTACTIC BODY RADIOTHERAPY; 2ND PRIMARY HEAD; LOCALLY RECURRENT HEAD; INTENSITY-MODULATED RADIOTHERAPY; PREVIOUSLY IRRADIATED HEAD; SQUAMOUS-CELL CARCINOMA; CONCURRENT CHEMOTHERAPY; RADIATION-THERAPY; DISEASE-CONTROL; CANCER;
D O I
10.1016/j.critrevonc.2020.103088
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aim: To provide a literature review on risk factors and strategies to prevent acute carotid blowout (CBO) syndrome in patients who underwent reirradiation (reRT) for recurrent head and neck (HN) malignancies. Patients and Methods: Inclusion criteria were: 1) CBO following reRT in the HN region, 2) description on patient-, tumor- or treatment-related risk factors, 3) clinical or radiological signs of threatened or impending CBO, and 4) CBO prevention strategies. Results: Thirty-five studies were selected for the analysis from five hundred seventy-seven records. Results provided indications on clinical, radiological and dosimetric parameters possibly associated with higher risk of CBO. Endovascular procedures (artery occlusion and stenting) to prevent acute massive hemorrhage in high risk patients were discussed. Conclusion: Literature data are still scarce with a low level of evidence. Nevertheless, the present work provides a comprehensive review useful for clinicians as a multidisciplinary pragmatic tool in their clinical practice.
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页数:11
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