The genetic control of succulent leaf development

Succulent leaves have long intrigued biologists; much research has been done to define succulence, understand the evolutionary trajectory and implications of leaf succulence, and contextualize the ecological importance of water storage for plants inhabiting dry habitats, particularly those using CAM photosynthesis. Surprisingly little is understood about the molecular regulation of leaf succulence, despite advances in our understanding of the molecular foundation of leaf architecture in model systems. Moreover, leaf succulence is a drought avoidance trait, one that has yet to be fully used for crop improvement. Here, connections between disparate literatures are highlighted: research on the regulation of cell size, the determination of vascular patterning, and water transport between cells have direct implications for our understanding of leaf succulence. Connecting functional genomics of leaf patterning with knowledge of the evolution and ecology of succulent species will guide future research on the determination and maintenance of leaf succulence.