Coding of pleasant touch by unmyelinated afferents in humans

被引：727

作者：

Loken, Line S. ^{[1
,2
]}

Wessberg, Johan ^{[1
]}

Morrison, India ^{[1
,2
]}

McGlone, Francis ^{[3
,4
]}

Olausson, Hakan ^{[1
,2
]}

机构：

[1] Univ Gothenburg, Inst Neurosci & Physiol, Gothenburg, Sweden

[2] Sahlgrens Univ Hosp, Dept Clin Neurophysiol, S-41345 Gothenburg, Sweden

[3] Univ Liverpool, Dept Neurol Sci, Liverpool L69 3BX, Merseyside, England

[4] Unilever R&D, Sensat Percept & Behav Grp, Wirral, Cheshire, England

来源：

NATURE NEUROSCIENCE | 2009年 / 12卷 / 05期

基金：

瑞典研究理事会;

关键词：

HUMAN HAIRY SKIN; TACTILE AFFERENTS; PAIN; PSYCHOPHYSICS; PLEASURE;

D O I：

10.1038/nn.2312

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Pleasant touch sensations may begin with neural coding in the periphery by specific afferents. We found that during soft brush stroking, low-threshold unmyelinated mechanoreceptors (C-tactile), but not myelinated afferents, responded most vigorously at intermediate brushing velocities (1-10 cm s(-1)), which were perceived by subjects as being the most pleasant. Our results indicate that C-tactile afferents constitute a privileged peripheral pathway for pleasant tactile stimulation that is likely to signal affiliative social body contact.

引用

页码：547 / 548

页数：2

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