Treatment of Retinoblastoma in 2015 Agreement and Disagreement

被引：177

作者：

Abramson, David H. ^{[1
,2
]}

Shields, Carol L. ^{[3
]}

Munier, Francis L. ^{[4
]}

Chantada, Guillermo L. ^{[5
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, New York, NY 10065 USA

[2] Weill Cornell Med Ctr, Dept Ophthalmol, New York, NY USA

[3] Thomas Jefferson Univ, Wills Eye Hosp, Ocular Oncol Serv, Philadelphia, PA 19107 USA

[4] Jules Gonin Eye Hosp, Fac Biol & Med Lausanne, Lausanne, Switzerland

[5] Hosp JP Garrahan, Res Inst, Buenos Aires, DF, Argentina

来源：

JAMA OPHTHALMOLOGY | 2015年 / 133卷 / 11期

关键词：

OPHTHALMIC ARTERY CHEMOTHERAPY; 2ND NONOCULAR TUMORS; INTRAARTERIAL CHEMOTHERAPY; INTRAOCULAR RETINOBLASTOMA; BILATERAL RETINOBLASTOMA; INTRAVITREAL INJECTION; CURRENT MANAGEMENT; RETINAL FUNCTION; PHASE-I/II; THERAPY;

D O I：

10.1001/jamaophthalmol.2015.3108

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The management of intraocular retinoblastoma is rapidly changing, and even recent reviews on the subject are behind existing practices. The 4 authors of this report collectively represent their management strategies with an emphasis on areas of agreement and disagreement. Ophthalmic artery chemosurgery and intravitreous chemotherapy have completely replaced external beam radiotherapy, reduced the use of systemic chemotherapy, and diminished enucleations by 90% without evidence of compromising patient survival.

引用

页码：1341 / 1347

页数：7

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