PHARMACOLOGICAL RESCUE OF MUTANT CFTR: EXPLORING MUTANT-SPECIFIC THERAPIES

被引:0
|
作者
Cholon, D. M. [1 ]
Quinney, N. L. [1 ]
Chaudhry, I. G. [1 ]
Guimbellot, J. S. [1 ]
Chua, M. [1 ]
Boyles, S. E. [1 ]
Houck, S. A. [1 ]
Dokholyan, N., V [1 ]
Randell, S. H. [1 ]
Gentzsch, M. [1 ]
机构
[1] Univ N Carolina, Cyst Fibrosis Res Ctr, Marsico Lung Inst, Chapel Hill, NC USA
关键词
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
6
引用
收藏
页码:194 / 195
页数:2
相关论文
共 50 条
  • [1] Influence of cell background on pharmacological rescue of mutant CFTR
    Pedemonte, Nicoletta
    Tomati, Valeria
    Sondo, Elvira
    Galietta, Luis J. V.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2010, 298 (04): : C866 - C874
  • [2] Mutant-specific gene programs in the zebrafish
    Weber, GJ
    Choe, SE
    Dooley, KA
    Paffett-Lugassy, NN
    Zhou, Y
    Zon, LI
    BLOOD, 2005, 106 (02) : 521 - 530
  • [3] Airway Epithelial Inflammation In Vitro Augments the Rescue of Mutant CFTR by Current CFTR Modulator Therapies
    Gentzsch, Martina
    Cholon, Deborah M.
    Quinney, Nancy L.
    Martino, Mary E. B.
    Minges, John T.
    Boyles, Susan E.
    Lee, Tara N. Guhr
    Esther, Charles R., Jr.
    Ribeiro, Carla M. P.
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [4] PROBLEMS AND OPPORTUNITIES IN MUTANT CFTR RESCUE
    Galietta, Luis J.
    PEDIATRIC PULMONOLOGY, 2009, : 151 - 152
  • [5] Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus
    Gianotti, Ambra
    Capurro, Valeria
    Scudieri, Paolo
    Galietta, Luis J. V.
    Moran, Oscar
    Zegarra-Moran, Olga
    JOURNAL OF CYSTIC FIBROSIS, 2016, 15 (03) : 295 - 301
  • [6] Pharmacological correctors of mutant CFTR mistrafficking
    Pedemonte, Nicoletta
    Galietta, Luis J. V.
    FRONTIERS IN PHARMACOLOGY, 2012, 3
  • [7] Pharmacological rescue of mutant ion channels
    Bezzina, CR
    Tan, HL
    CARDIOVASCULAR RESEARCH, 2002, 55 (02) : 229 - 232
  • [8] ALLOSTERIC INHIBITORS TARGET KRAS IN A MUTANT-SPECIFIC MANNER
    不详
    CANCER DISCOVERY, 2014, 4 (01) : 17 - 17
  • [9] Targeting Mutant KRAS with Novel Mutant-Specific Pharmacological Inhibitors: Activity Against Myeloma and Other Lymphoid Malignant Cells and Molecular Mechanisms of Resistance
    Steinbrunn, Torsten
    Shirasaki, Ryosuke
    Dashevsky, Olga
    Tang, Huihui
    Yamano, Shizuka
    Mizuno, Rin
    Sugihara, Takeru
    Teoh, Phaik Ju
    Leypoldt, Lisa B.
    Kaji, Mariko
    Sorrell, Jeffrey
    Glassner, Brian J.
    Simoes, Ricardo De Matos
    Christensen, James
    Mitsiades, Constantine S.
    BLOOD, 2023, 142
  • [10] α-Synuclein Disrupts Vesicle Fusion by Two Mutant-Specific Mechanisms
    Yoo, Gyeongji
    An, Hyeong Jeon
    Yeou, Sanghun
    Lee, Nam Ki
    MOLECULES AND CELLS, 2022, 45 (11) : 806 - 819