Iron(III)-salan complexes catalysed highly enantioselective fluorination and hydroxylation of β-keto esters and N-Boc oxindoles

被引：103

作者：

Gu, Xin ^{[1
]}

Zhang, Yan ^{[1
]}

Xu, Zhen-Jiang ^{[1
]}

Che, Chi-Ming ^{[1
,2
,3
]}

机构：

[1] Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai, Peoples R China

[2] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[3] Univ Hong Kong, State Key Lab Synthet Chem, Hong Kong, Hong Kong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 58期

关键词：

C-H ACTIVATION; CARBONYL-COMPOUNDS; ALPHA-HYDROXYLATION; CIS-DIHYDROXYLATION; MECHANISTIC ASPECTS; HYDROGEN-PEROXIDE; ORGANIC-SYNTHESIS; DFT CALCULATIONS; IRON COMPLEXES; BOND AMINATION;

D O I：

10.1039/c4cc01631a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral iron(III)-salan complexes catalysed highly enantioselective alpha-fluorination and alpha-hydroxylation of beta-keto esters and N-Boc oxindoles to give the corresponding products in high yields and good-to-excellent ee values under mild reaction conditions.

引用

页码：7870 / 7873

页数：4

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