The patient with megaesophagus due to long-term achalasia combined with squamous cell carcinoma: A case report

Introduction: Achalasia is a rare disease of the esophagus accompanied by progressive development of symptoms such as dysphagia, vomiting, and chest pain, which in case of ineffective treatment leads to the formation of megaesophagus and requires radical surgical treatment. The relationship between the lengthy course of esophageal achalasia and the chance of developing esophageal cancer has been evidenced in the international literature.Presentation of case: This paper presents a case of a patient with long-term (30 years) achalasia, grade 4 dysphagia, and severe concomitant cardiovascular pathology who was diagnosed with megaesophagus and carcinoma of the lower thoracic esophagus after receiving solely symptomatic treatment. The patient underwent a video-assisted thoracoscopic K.C. McKeown esophagectomy, two-field lymphadenectomy, and esophageal gastroplasty. The postoperative period proceeded without complications. Ten months post-surgery there were no signs of recurrence or progression of the disease. The patient also noted a decrease in cardiac symptoms.Discussion: Clinical manifestations of achalasia are characterized by progressive dysphagia, predominant nocturnal regurgitation, aspiration of undigested food, and weight loss. The role of cancer surveillance in achalasia remains controversial. Medical therapy and minimally invasive interventions can be used for both early and late stages of the disease. The use of minimally invasive techniques for the megaesophagus is recognized as ineffective and increases the risk of post-manipulation complications.Conclusion: Since minimally invasive techniques are ineffective, radical surgical treatment, or esophagectomy, appears to be the best choice in case of the development of megaesophagus and the detection of esophageal cancer.