AP-1 Takes Centre Stage in Enhancer Chromatin Dynamics

被引：45

作者：

Madrigal, Pedro ^{[1
,2
]}

Alasoo, Kaur ^{[3
]}

机构：

[1] Wellcome Sanger Inst, Hinxton CB10 1SA, England

[2] Univ Cambridge, Dept Physiol Dev & Neurosci, Ctr Trophoblast Res, Cambridge CB2 3EG, England

[3] Univ Tartu, Inst Comp Sci, EE-50409 Tartu, Estonia

来源：

TRENDS IN CELL BIOLOGY | 2018年 / 28卷 / 07期

关键词：

TRANSCRIPTION FACTORS; ACCESSIBILITY DYNAMICS; METASTASIS; MACROPHAGE; BINDING;

D O I：

10.1016/j.tcb.2018.04.009

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent studies involving induced pluripotent stem cell (iPSC) reprogramming in mice and monocyte-to-macrophage differentiation in humans have revealed a role for the transcription factor (TF) activator protein 1 (AP-1) in chromatin accessibility. Enhancer selection may be determined not only by cell type-specific sets of TFs but also by broadly expressed ones like AP-1.

引用

页码：509 / 511

页数：3

共 15 条

[1] Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding [J].

Biddie, Simon C. ;

John, Sam ;

Sabo, Pete J. ;

Thurman, Robert E. ;

Johnson, Thomas A. ;

Schiltz, R. Louis ;

Miranda, Tina B. ;

Sung, Myong-Hee ;

Trump, Saskia ;

Lightman, Stafford L. ;

Vinson, Charles ;

Stamatoyannopoulos, John A. ;

Hager, Gordon L. .

MOLECULAR CELL, 2011, 43 (01) :145-155

[2] Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma [J].

Britton, Edward ;

Rogerson, Connor ;

Mehta, Shaveta ;

Li, Yaoyong ;

Li, Xiaodun ;

Fitzgerald, Rebecca C. ;

Ang, Yeng S. ;

Sharrocks, Andrew D. .

PLOS GENETICS, 2017, 13 (08)

[3] Single-cell chromatin accessibility reveals principles of regulatory variation [J].

Buenostro, Jason D. ;

Wu, Beijing ;

Litzenburger, Ulrike M. ;

Ruff, Dave ;

Gonzales, Michael L. ;

Snyder, Michael P. ;

Chang, Howard Y. ;

Greenleaf, William J. .

NATURE, 2015, 523 (7561) :486-U264

[4] Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [J].

Cao, Shangtao ;

Yu, Shengyong ;

Li, Dongwei ;

Ye, Jing ;

Yang, Xuejie ;

Li, Chen ;

Wang, Xiaoshan ;

Mai, Yuanbang ;

Qin, Yue ;

Wu, Jian ;

He, Jiangping ;

Zhou, Chunhua ;

Liu, He ;

Zhao, Bentian ;

Shu, Xiaodong ;

Wu, Chuman ;

Chen, Ruiping ;

Chan, Waiyee ;

Pan, Guangjin ;

Chen, Jiekai ;

Liu, Jing ;

Pei, Duanqing .

CELL STEM CELL, 2018, 22 (04) :529-+

[5] Cooperative Binding of Transcription Factors Orchestrates Reprogramming [J].

Chronis, Constantinos ;

Fiziev, Petko ;

Papp, Bernadett ;

Butz, Stefan ;

Bonora, Giancarlo ;

Sabri, Shan ;

Ernst, Jason ;

Plath, Kathrin .

CELL, 2017, 168 (03) :442-+

[6] Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility [J].

Denny, Sarah K. ;

Yang, Dian ;

Chuang, Chen-Hua ;

Brady, Jennifer J. ;

Lim, Jing Shan ;

Gruner, Barbara M. ;

Chiou, Shin-Heng ;

Schep, Alicia N. ;

Baral, Jessika ;

Hamard, Cecile ;

Antoine, Martine ;

Wislez, Marie ;

Kong, Christina S. ;

Connolly, Andrew J. ;

Park, Kwon-Sik ;

Sage, Julien ;

Greenleaf, William J. ;

Winslow, Monte M. .

CELL, 2016, 166 (02) :328-342

[7] Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities [J].

Heinz, Sven ;

Benner, Christopher ;

Spann, Nathanael ;

Bertolino, Eric ;

Lin, Yin C. ;

Laslo, Peter ;

Cheng, Jason X. ;

Murre, Cornelis ;

Singh, Harinder ;

Glass, Christopher K. .

MOLECULAR CELL, 2010, 38 (04) :576-589

[8] Pioneer transcription factors in cell reprogramming [J].

Iwafuchi-Doi, Makiko ;

Zaret, Kenneth S. .

GENES & DEVELOPMENT, 2014, 28 (24) :2679-2692

[9] Chromatin Loop Formation in the β-Globin Locus and Its Role in Globin Gene Transcription [J].

Kim, AeRi ;

Dean, Ann .

MOLECULES AND CELLS, 2012, 34 (01) :1-5

[10] Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming [J].

Knaupp, Anja S. ;

Buckberry, Sam ;

Pflueger, Jahnvi ;

Lim, Sue Mei ;

Ford, Ethan ;

Larcombe, Michael R. ;

Rossello, Fernando J. ;

de Mendoza, Alex ;

Alaei, Sara ;

Firas, Jaber ;

Holmes, Melissa L. ;

Nair, Shalima S. ;

Clark, Susan J. ;

Nefzger, Christian M. ;

Lister, Ryan ;

Polo, Jose M. .

CELL STEM CELL, 2017, 21 (06) :834-+

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