COVID-19 and the kidney

被引：52

作者：

Hassanein, Mohamed ^{[1
]}

Radhakrishnan, Yeshwanter ^{[1
,2
]}

Sedor, John ^{[1
,3
]}

Vachharajani, Tushar ^{[3
]}

Vachharajani, Vidula T. ^{[3
,4
]}

Augustine, Joshua ^{[1
,3
]}

Demirjian, Sevag ^{[1
,3
]}

Thomas, George ^{[1
,3
]}

机构：

[1] Cleveland Clin, Dept Nephrol & Hypertens, Glickman Urol & Kidney Inst, Cleveland, OH 44106 USA

[2] Cleveland Clin Akron Gen, Akron, OH USA

[3] Case Western Reserve Univ, Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA

[4] Cleveland Clin, Dept Crit Care Med, Resp Inst, Cleveland, OH 44106 USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2020年 / 87卷 / 10期

关键词：

ANGIOTENSIN-CONVERTING ENZYME; NEW-YORK-CITY; CLINICAL CHARACTERISTICS; HOSPITALIZED-PATIENTS; INJURY; INFECTION; DIALYSIS; MANAGEMENT; PNEUMONIA; OUTCOMES;

D O I：

10.3949/ccjm.87a.20072

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

COVID-19 is primarily considered a respiratory illness, but the kidney may be one of the targets of SARS-CoV-2 infection, since the virus enters cells through the angiotensin-converting enzyme 2 receptor, which is found in abundance in the kidney. Information on kidney involvement in COVID-19 is limited but is evolving rapidly. This article discusses the pathogenesis of acute kidney injury (AKI) in COVID-19, its optimal management, and the impact of COVID-19 on patients with chronic kidney disease, patients with end-stage kidney disease on dialysis, and kidney transplant recipients.

引用

页码：619 / 631

页数：13

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