Language and Literacy Development in Individuals With Velo-cardio-facial Syndrome

被引：6
|
作者：
Antshel, Kevin M. [1 ]
Marrinan, Eileen [2 ]
Kates, Wendy R. [1 ]
Fremont, Wanda [1 ]
Shprintzen, Robert J. [2 ]
机构：
[1] SUNY Upstate Med Univ, Dept Psychiat & Behav Sci, Syracuse, NY 13210 USA
[2] SUNY Upstate Med Univ, Dept Otolaryngol & Commun Sci, Syracuse, NY 13210 USA
来源：
TOPICS IN LANGUAGE DISORDERS | 2009年 / 29卷 / 02期
关键词：
genetic syndrome; language; literacy; 22q11.2 deletion syndrome; VCFS; 22Q11.2 DELETION SYNDROME; SUBMUCOUS CLEFT-PALATE; VELOCARDIOFACIAL SYNDROME VCFS; VASCULAR DISRUPTION SEQUENCE; FUNCTIONAL COMT POLYMORPHISM; SHORT-TERM-MEMORY; OTITIS-MEDIA; WILLIAMS-SYNDROME; NEUROCOGNITIVE PHENOTYPE; PREPULSE INHIBITION;
D O I：
10.1097/TLD.0b013e3181a72084
中图分类号：
H0 [语言学];
学科分类号：
030303 ; 0501 ; 050102 ;
摘要：
Velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion of chromosome 22q11.2. Although there is some variability, VCFS is associated with a characteristic physical, behavioral, and cognitive phenotype. This review article focuses on aspects of language and literacy development in VCFS, describing what is known and offering avenues for future research. The most consistently reported language and literacy findings in the VCFS population include reading, spelling, phonological processing, and auditory verbal rote memory abilities as areas of relative strength. Receptive language abilities are noted to be relatively stronger than expressive language abilities in individuals with VCFS. Speech disorders are very common in VCFS, and the most common compensatory articulation substitution in VCFS is the glottal stop.
引用
收藏
页码：170 / 186
页数：17
相关论文
共 50 条
  • [11] Retrospective analysis of feeding and speech disorders in 50 patients with velo-cardio-facial syndrome
    Rommel, N
    Vantrappen, G
    Swillen, A
    Devriendt, K
    Feenstra, L
    Fryns, JP
    GENETIC COUNSELING, 1999, 10 (01): : 71 - 78
  • [12] THE VELO-CARDIO-FACIAL SYNDROME: THE SPECTRUM OF PSYCHIATRIC PROBLEMS AND COGNITIVE DETERIORATION AT ADULT AGE
    Evers, L. J. M.
    De Die-Smulders, C. E. M.
    Smeets, E. E. J.
    Clerkx, M. G. M.
    Curfs, L. M. G.
    GENETIC COUNSELING, 2009, 20 (04): : 307 - 316
  • [13] Velo-Cardio-Facial syndrome: Clinical report of a 70-year-old woman
    Verhoeven, WMA
    Tuinier, S
    Engelen, JJM
    Hollanders-Crombach, HTM
    Curfs, LMG
    AMERICAN JOURNAL OF MEDICAL GENETICS, 2002, 111 (04): : 409 - 411
  • [14] Cleft palate, retrognathia and congenital heart disease in velo-cardio-facial syndrome: A phenotype correlation study
    Friedman, Marcia A.
    Miletta, Nathanial
    Roe, Cheryl
    Wang, Dongliang
    Morrow, Bernice E.
    Kates, Wendy R.
    Higgins, Anne Marie
    Shprintzen, Robert J.
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2011, 75 (09) : 1167 - 1172
  • [15] Cervical vascular and upper airway asymmetry in velo-cardio-facial syndrome: Correlation of nasopharyngoscopy with MRA
    Oppenheimer, Avi G.
    Fulmer, Susan
    Shifteh, Keivan
    Chang, Ja-Kwei
    Brook, Allan
    Shanske, Alan L.
    Shprintzen, Robert J.
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2010, 74 (06) : 619 - 625
  • [16] Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndrome
    van Amelsvoort, T.
    Zinkstok, J.
    Figee, M.
    Daly, E.
    Morris, R.
    Owen, M. J.
    Murphy, K. C.
    De Haan, L.
    Linszen, D. H.
    Glaser, B.
    Murphy, D. G. M.
    PSYCHOLOGICAL MEDICINE, 2008, 38 (01) : 89 - 100
  • [17] Cortical gyrification in velo-cardio-facial (22q11.2 deletion) syndrome: A longitudinal study
    Kunwar, Arun
    Ramanathan, Seethalakshmi
    Nelson, Joshua
    Antshel, Kevin M.
    Fremont, Wanda
    Higgins, Anne Marie
    Shprintzen, Robert J.
    Kates, Wendy R.
    SCHIZOPHRENIA RESEARCH, 2012, 137 (1-3) : 20 - 25
  • [18] Atlas-based white matter analysis in individuals with velo-cardio-facial syndrome (22q11.2 deletion syndrome) and unaffected siblings
    Petya D Radoeva
    Ioana L Coman
    Kevin M Antshel
    Wanda Fremont
    Christopher S McCarthy
    Ashwini Kotkar
    Dongliang Wang
    Robert J Shprintzen
    Wendy R Kates
    Behavioral and Brain Functions, 8
  • [19] Atlas-based white matter analysis in individuals with velo-cardio-facial syndrome (22q11.2 deletion syndrome) and unaffected siblings
    Radoeva, Petya D.
    Coman, Ioana L.
    Antshel, Kevin M.
    Fremont, Wanda
    McCarthy, Christopher S.
    Kotkar, Ashwini
    Wang, Dongliang
    Shprintzen, Robert J.
    Kates, Wendy R.
    BEHAVIORAL AND BRAIN FUNCTIONS, 2012, 8
  • [20] Abnormal patterns of cortical gyrification in velo-cardio-facial syndrome (deletion 22q11.2): An MRI study
    Schaer, M
    Schmitt, JE
    Glaser, B
    Lazeyras, F
    Delavelle, J
    Eliez, S
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2006, 146 (01) : 1 - 11
12345