HISTONE H3 WILD-TYPE DIPG/DMG OVEREXPRESSING EZHIP EXTEND THE SPECTRUM OF DIFFUSE MIDLINE GLIOMAS WITH PRC2 INHIBITION BEYOND H3-K27M MUTATION

被引：0
|
作者：
Castel, David [1 ]
Kergrohen, Thomas [1 ]
Tauziede-Espariat, Arnault [2 ]
Mackay, Alan [3 ]
Ghermaoui, Samia [1 ]
Lechapt, Emmanuele [2 ]
Pfister, Stefan [4 ]
Kramm, Christof [5 ]
Boddaert, Nathalie
Blauwblomme, Thomas [6 ]
Puget, Stephanie [6 ]
Beccaria, Kevin [6 ]
Jones, Chris [3 ]
Jones, David [4 ]
Varlet, Pascale [2 ]
Grill, Jacques [1 ]
Debily, Marie-Anne [1 ]
机构：
[1] Gustave Roussy, Villejuif, France
[2] GHU Paris Psychiat Neurosci, Paris, France
[3] Inst Canc Res, London, England
[4] German Canc Res Ctr, Heidelberg, Germany
[5] Univ Med Ctr, Gottingen, Germany
[6] Hop Necker Enfants Malad, Paris, France
来源：
NEURO-ONCOLOGY | 2020年 / 22卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
DIPG-58
引用
收藏
页码：298 / 298
页数：1
相关论文
共 50 条
  • [31] Differentiation between spinal cord diffuse midline glioma with histone H3 K27M mutation and wild type: comparative magnetic resonance imaging
    Jo Sung Jung
    Yoon Seong Choi
    Sung Soo Ahn
    Seong Yi
    Se Hoon Kim
    Seung-Koo Lee
    Neuroradiology, 2019, 61 : 313 - 322
  • [32] Differentiation between spinal cord diffuse midline glioma with histone H3 K27M mutation and wild type: comparative magnetic resonance imaging
    Jung, Jo Sung
    Choi, Yoon Seong
    Ahn, Sung Soo
    Yi, Seong
    Kim, Se Hoon
    Lee, Seung-Koo
    NEURORADIOLOGY, 2019, 61 (03) : 313 - 322
  • [33] A case of diffuse midline glioma with histone H3 K27M mutation mimicking long segmental myelitis
    Lin, Hsin-Pin
    Zhao, Cuiping
    Viswanathan, Vyas
    Yachnis, Anthony T.
    Wymer, James
    INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT, 2021, 23
  • [34] PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism
    Siddhant U. Jain
    Truman J. Do
    Peder J. Lund
    Andrew Q. Rashoff
    Katharine L. Diehl
    Marcin Cieslik
    Andrea Bajic
    Nikoleta Juretic
    Shriya Deshmukh
    Sriram Venneti
    Tom W. Muir
    Benjamin A. Garcia
    Nada Jabado
    Peter W. Lewis
    Nature Communications, 10
  • [35] DIFFUSION CHARACTERISTICS OF PEDIATRIC DIFFUSE MIDLINE GLIOMAS WITH HISTONE H3 K27M MUTATION USING APPARENT DIFFUSION COEFFICIENT HISTOGRAM ANALYSIS
    Aboian, Mariam
    Solomon, David A.
    Kline-Nunnally, Cassie
    Vardapetyan, Anna
    Tong, Elizabeth
    Li, Yi
    Felton, Erin
    Braunstein, Steve
    Mueller, Sabine
    Cha, Soonmee
    NEURO-ONCOLOGY, 2017, 19 : 158 - 158
  • [36] PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism
    Jain, Siddhant U.
    Do, Truman J.
    Lund, Peder J.
    Rashoff, Andrew Q.
    Diehl, Katharine L.
    Cieslik, Marcin
    Bajic, Andrea
    Juretic, Nikoleta
    Deshmukh, Shriya
    Venneti, Sriram
    Muir, Tom W.
    Garcia, Benjamin A.
    Jabado, Nada
    Lewis, Peter W.
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [37] Diffuse hemispheric glioma with H3 p.K28M (K27M) mutation: Unusual non-midline presentation of diffuse midline glioma, H3 K27M-altered?
    Donev, Kliment
    Sundararajan, Vanitha
    Johnson, Derek
    Balan, Jagadheshwar
    Chambers, Meagan
    Paulson, Vera A.
    Scherpelz, Kathryn P.
    Abdullaev, Zied
    Quezado, Martha
    Cimino, Patrick J.
    Pratt, Drew
    Valerio, Ediel
    de Castro, Joao Victor Alves
    Carraro, Dirce Maria
    Torrezan, Giovana Tardin
    Wolff, Beatriz Martins
    Kulikowski, Leslie Domenici
    Costa, Felipe D'Almeida
    Aldape, Kenneth
    Ida, Cristiane M.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2024, 83 (05): : 357 - 364
  • [38] Transcriptomic and epigenetic profiling of "diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location
    Castel, David
    Philippe, Cathy
    Kergrohen, Thomas
    Sill, Martin
    Merlevede, Jane
    Barret, Emilie
    Puget, Stephanie
    Sainte-Rose, Christian
    Kramm, Christof M.
    Jones, Chris
    Varlet, Pascale
    Pfister, Stefan M.
    Grill, Jacques
    Jones, David T. W.
    Debily, Marie-Anne
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2018, 6 : 117
  • [39] Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location
    David Castel
    Cathy Philippe
    Thomas Kergrohen
    Martin Sill
    Jane Merlevede
    Emilie Barret
    Stéphanie Puget
    Christian Sainte-Rose
    Christof M. Kramm
    Chris Jones
    Pascale Varlet
    Stefan M. Pfister
    Jacques Grill
    David T. W. Jones
    Marie-Anne Debily
    Acta Neuropathologica Communications, 6
  • [40] CLINICAL AND MOLECULAR CHARACTERIZATION OF ADULT DIFFUSE MIDLINE GLIOMAS, H3 K27M-MUTANT
    Grassl, N.
    Suwala, A.
    Kessler, T.
    Etminan, N.
    Unterberg, A.
    Breckwoldt, M.
    Bendszus, M.
    Groden, C.
    Debus, J.
    Ehmann, M.
    Wick, W.
    Sahm, F.
    Platten, M.
    Sahm, K.
    NEURO-ONCOLOGY, 2024, 26
12345