Antimicrobial gallic acid from Caesalpinia mimosoides Lamk.

被引:204
作者
Chanwitheesuk, Anchana
Teerawutgulrag, Aphiwat
Kilburn, Jeremy D.
Rakariyatham, Nuansri [1 ]
机构
[1] Chiang Mai Univ, Fac Sci, Dept Chem, Chiang Mai 50200, Thailand
[2] Univ Southampton, Sch Chem, Southampton SO17 1PQ, Hants, England
关键词
Caesalpinia mimosoides; antimicrobial activity; gallic acid;
D O I
10.1016/j.foodchem.2005.11.008
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Different extracts of Caesalpinia mimosoides Lamk. (Leguminosae) were tested against eight human pathogenic bacteria and six fungal strains by the disc diffusion method. Among these extracts, the aqueous and the ethanolic extracts showed potent activity against some tested microorganisms. Subsequently, the latter extract was fractionated by means of Sephadex LH-20 column chromatography. A bioactive substance, responsible for the antimicrobial property was separated, and its structure was assigned as a known compound, gallic acid, by extensive chromatographic and spectroscopic analyses. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1044 / 1048
页数:5
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