Effects of Photobiomodulation on SOFAT, A T-cell-derived Cytokine, May Explain Accelerated Orthodontic Tooth Movement

被引:7
作者
Jettar, Viviane [1 ]
Napimoga, Marcelo H. [2 ]
Freitas, Fabiana [3 ]
Clemente-Napimoga, Juliana T. [4 ]
Suzuki, Selly S. [1 ]
Montalli, Victor A. [2 ]
Garcez, Aguinaldo S. [1 ]
机构
[1] Sao Leopoldo Mandic Inst & Res Ctr, Orthodont, Campinas, SP, Brazil
[2] Sao Leopoldo Mandic Inst & Res Ctr, Campinas, SP, Brazil
[3] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Physiol, Piracicaba, SP, Brazil
[4] Sao Leopoldo Mandic Inst & Res Ctr, Physiol, Campinas, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
LEVEL LASER THERAPY; SECRETED OSTEOCLASTOGENIC FACTOR; ROOT RESORPTION; MECHANICAL VIBRATION; RANKL; EXPRESSION; FORCE; OPG; ACTIVATOR; VELOCITY;
D O I
10.1111/php.12878
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Orthodontic tooth movement is based on mechanical forces inducing bone remodeling, and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFATa secreted osteoclastogenic factor of activated T cells and RANK-L during tooth movement. The results showed that tooth displacement, RANK-L and SOFAT levels were significantly greater compared to Control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity.
引用
收藏
页码:604 / 610
页数:7
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