Mycoplasma genitalium and Trichomonas vaginalis in France: a point prevalence study in people screened for sexually transmitted diseases

被引：33
作者：
Pereyre, S. [1 ,2 ,3 ]
Nadalie, C. Laurier [1 ,2 ]
Bebear, C. [1 ,2 ,3 ]
机构：
[1] Univ Bordeaux, Bordeaux, France
[2] INRA, Bordeaux, France
[3] Bordeaux Univ Hosp, Bordeaux, France
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2017年 / 23卷 / 02期
关键词：
France; Mycoplasma genitalium; Prevalence; Screening; Trichomonas vaginalis; REAL-TIME PCR; CHLAMYDIA-TRACHOMATIS; MACROLIDE RESISTANCE; NEISSERIA-GONORRHOEAE; WOMEN; URETHRITIS; GUIDELINE; CARE; MEN;
D O I：
10.1016/j.cmi.2016.10.028
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Objective: Mycoplasma genitalium and Trichomonas vaginalis are common causes of sexually transmitted infections, but limited prevalence data are available in France. We aimed to evaluate the prevalence of M. genitalium and T. vaginalis infections and to assess prevalence by gender, age, sample collection sites and clinical symptoms. A multicentre collection of specimens was intended to obtain a nationwide overview of the epidemiology. Methods: Between September 2014 and January 2015, a total of 2652 consecutive urogenital specimens submitted to the microbiology diagnostic departments of 16 French university hospitals for Chlamydia trachomatis and Neisseria gonorrhoeae detection were collected. M. genitalium and T. vaginalis prevalence were evaluated using a commercial real-time PCR kit. Clinical data from patients were anonymously collected. Results: T. vaginalis and M. genitalium prevalence were 1.7% (95% confidence interval 1.3-2.4) and 3.4% (95% confidence interval 2.8-4.2), respectively, and did not differ between gender or age groups, except M. genitalium prevalence between men and women in the 35-to 44-year age group (5.9 vs. 1.5%; p 0.03). M. genitalium prevalence was significantly higher in patients receiving care in sexually transmitted infection clinics, abortion centres, family planning clinics and prisons than in gynaecologic, obstetric and reproduction centres (4.0 vs. 1.7%, p 0.009). Among M. genitalium-and T. vaginalis-positive patients, 70.9 and 61.5% were asymptomatic, respectively. Conclusions: The lowT. vaginalis prevalence does not justify systematic screening for this organismin France. Conversely, selective screening for M. genitalium may be warranted in care settings that receive presumably high-risk sexual behaviour patients, regardless of symptoms. (C) 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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页码：122.e1 / 122.e7
页数：7
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