4-hydroxy-2-quinolones 151. Reaction of 4-chloro-3-ethoxycarbonyl-2-oxo-1,2-dihydroquinolines with p-toluenesulfonylhydrazide

被引：3

作者：

Ukrainets, I. V. ^{[1
]}

Tkach, A. A. ^{[1
]}

Kravtsova, V. V. ^{[1
]}

Turov, A. V. ^{[2
]}

机构：

[1] Natl Univ Pharm, UA-61002 Kharkov, Ukraine

[2] Taras Shevchenko Kiev Natl Univ, UA-01033 Kiev, Ukraine

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2009年 / 45卷 / 01期

关键词：

1,5-dihydropyrazolo[4,3-c]quinolin-4-ones; 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylates; p-toluenesulfonylhydrazide; alkylation; X-ray structural analysis; MOLECULAR-STRUCTURE; CRYSTAL;

D O I：

10.1007/s10593-009-0224-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of ethyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate with p-toluene-sulfonylhydrazide at room temperature in the system DMSO/K2CO3 gives 5-methyl-2-(toluene-4-sulfonyl)-1,2-dihydro-5H-pyrazolo[4,3-c]quinoline-3,4-dione, alkylation of which using ethyl iodide gives the 1N-substituted derivative.

引用

页码：48 / 54

页数：7