Centella asiatica in Dermatology: An Overview

被引：159

作者：

Bylka, Wieslawa ^{[1
]}

Znajdek-Awizen, Paulina ^{[1
]}

Studzinska-Sroka, Elzbieta ^{[1
]}

Danczak-Pazdrowska, Aleksandra ^{[2
]}

Brzezinska, Malgorzata ^{[1
]}

机构：

[1] Poznan Univ Med Sci, Dept Pharmacognosy, PL-60781 Poznan, Poland

[2] Poznan Univ Med Sci, Dept Dermatol, PL-60355 Poznan, Poland

来源：

PHYTOTHERAPY RESEARCH | 2014年 / 28卷 / 08期

关键词：

Centella asiatica; triterpenes; review; dermatology; COLLAGEN-I SYNTHESIS; FIBROBLAST-CULTURES; L; URBAN; VITRO; RAT; TRITERPENOIDS; EXPRESSION; INDUCTION; EXTRACTS; MODELS;

D O I：

10.1002/ptr.5110

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Centella asiatica is a medicinal plant that was already used as a panacea' 3000 years ago. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecasosside, asiatic acid and madecassic acid. We have conducted an overview to summarize current knowledge on the results of scientific in vitro and in vivo experiments focused on the improvement of the healing process of small wounds, hypertrophic scars and burns by C. asiatica. In this paper, we discuss the data on constituents, recommended preparations and the potential side effects of C. asiatica. Copyright (c) 2014 John Wiley & Sons, Ltd.

引用

页码：1117 / 1124

页数：8

共 43 条

[21] Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model [J].

Lee, Jeong-Hyun ;

Kim, Hye-Lee ;

Lee, Mi Hee ;

You, Kyung Eun ;

Kwon, Byeong-Ju ;

Seo, Hyok Jin ;

Park, Jong-Chul .

PHYTOMEDICINE, 2012, 19 (13) :1223-1227

[22] Madecassoside isolated from Centello asiatica herbs facilitates burn wound healing in mice [J].

Liu, Mei ;

Dai, Yue ;

Li, Ying ;

Luo, Yubin ;

Huang, Fang ;

Gong, Zhunan ;

Meng, Qingyu .

PLANTA MEDICA, 2008, 74 (08) :809-815

[23] Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts [J].

Lu, L ;

Ying, K ;

Wei, SM ;

Fang, Y ;

Liu, YL ;

Lin, HF ;

Ma, LJ ;

Mao, YM .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2004, 43 (11) :801-807

[24] Dermal fibroblast-associated gene induction by asiaticoside shown in vitro by DNA microarray analysis [J].

Lu, L ;

Ying, K ;

Wei, S ;

Liu, Y ;

Lin, H ;

Mao, Y .

BRITISH JOURNAL OF DERMATOLOGY, 2004, 151 (03) :571-578

[25] STIMULATION OF COLLAGEN-SYNTHESIS IN FIBROBLAST-CULTURES BY A TRITERPENE EXTRACTED FROM CENTELLA-ASIATICA [J].

MAQUART, FX ;

BELLON, G ;

GILLERY, P ;

WEGROWSKI, Y ;

BOREL, JP .

CONNECTIVE TISSUE RESEARCH, 1990, 24 (02) :107-120

[26]

Maquart FX, 1999, EUR J DERMATOL, V9, P289

[27] A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-α in activated RAW 264.7 cells [J].

Nguyen Xuan Nhiem ;

Bui Huu Tai ;

Tran Hong Quang ;

Phan Van Kiem ;

Chau Van Minh ;

Nguyen Hoai Nam ;

Kim, Jun-Ho ;

Im, Lee-Rang ;

Lee, Young-Mi ;

Kim, Young Ho .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (06) :1777-1781

[28] Asiaticoside Induces Type I Collagen Synthesis and Osteogenic Differentiation in Human Periodontal Ligament Cells [J].

Nowwarote, Nunthawan ;

Osathanon, Thanaphum ;

Jitjaturunt, Peachaya ;

Manopattanasoontorn, Sukuman ;

Pavasant, Prasit .

PHYTOTHERAPY RESEARCH, 2013, 27 (03) :457-462

[29]

O M., 2009, EUROPEAN J SCI RES, V30, P260

[30]

Paocharoen Veeraya, 2010, J Med Assoc Thai, V93 Suppl 7, pS166

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