Centella asiatica in Dermatology: An Overview

被引:159
作者
Bylka, Wieslawa [1 ]
Znajdek-Awizen, Paulina [1 ]
Studzinska-Sroka, Elzbieta [1 ]
Danczak-Pazdrowska, Aleksandra [2 ]
Brzezinska, Malgorzata [1 ]
机构
[1] Poznan Univ Med Sci, Dept Pharmacognosy, PL-60781 Poznan, Poland
[2] Poznan Univ Med Sci, Dept Dermatol, PL-60355 Poznan, Poland
关键词
Centella asiatica; triterpenes; review; dermatology; COLLAGEN-I SYNTHESIS; FIBROBLAST-CULTURES; L; URBAN; VITRO; RAT; TRITERPENOIDS; EXPRESSION; INDUCTION; EXTRACTS; MODELS;
D O I
10.1002/ptr.5110
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Centella asiatica is a medicinal plant that was already used as a panacea' 3000 years ago. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecasosside, asiatic acid and madecassic acid. We have conducted an overview to summarize current knowledge on the results of scientific in vitro and in vivo experiments focused on the improvement of the healing process of small wounds, hypertrophic scars and burns by C. asiatica. In this paper, we discuss the data on constituents, recommended preparations and the potential side effects of C. asiatica. Copyright (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:1117 / 1124
页数:8
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