Accidental Falls and Risk of Mortality among Older Adults on Chronic Peritoneal Dialysis

被引:27
作者
Farragher, Janine [1 ]
Chiu, Ernest [1 ]
Ulutas, Ozkan [1 ,2 ]
Tomlinson, George [3 ,4 ]
Cook, Wendy L. [5 ]
Jassal, Sarbjit V. [1 ,3 ,4 ]
机构
[1] Univ Hlth Network, Div Nephrol, Toronto, ON, Canada
[2] Inonu Univ, Fac Med, Div Nephrol, Malatya, Turkey
[3] Univ Hlth Network, Dept Med, Toronto, ON, Canada
[4] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada
[5] Univ British Columbia, Fac Med, Div Geriatr Med, Vancouver, BC, Canada
来源
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2014年 / 9卷 / 07期
关键词
HEMODIALYSIS-PATIENTS; FUNCTIONAL MOBILITY; GO TEST; PEOPLE; INJURIES; RESTRICTION;
D O I
10.2215/CJN.11001013
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Background and objectives More than 40% of elderly hemodialysis patients experience one or more accidental falls within a 1-year period. Such falls are associated with higher mortality. The objectives of this study were to assess whether falls are also common in elderly patients established on peritoneal dialysis and evaluate if patients with falls have a higher risk of mortality than patients who do not experience a fall. Design, setting, participants, & measurements Using a prospective cohort study design, patients ages years on chronic peritoneal dialysis from April 2002 to April 2003 at the University Health Network were recruited. Patients were followed biweekly, and falls occurring within the first 15 months were recorded. Outcome data were collected until death, study end (July 31, 2012), transplantation, or transfer to another dialysis center. Results Seventy-four of seventy-six potential patients were recruited, assessed at baseline, and followed biweekly for falls; 40 of 74 (54%) peritoneal dialysis patients experienced 89 falls (adjusted mean fall rate, 1.7 falls per patient-year; 95% confidence interval, 1.0 to 2.7). Patients with falls were more likely to have had previous falls, be more recently initiated onto dialysis, be men, be older, and have higher comorbidity. Twenty-eight patients died during the follow-up period. After adjustment for known risk factors, each successive fall was associated with a 1.62-fold higher mortality (hazard ratio, 1.62; 95% confidence interval, 1.29 to 2.02; P<0.001). Conclusions Accidental falls are common in the peritoneal dialysis population and often go unrecognized. Falls were associated with higher mortality risk. Because fall interventions are effective in other populations, screening peritoneal dialysis patients for falls may be a simple measure of clinical importance.
引用
收藏
页码:1248 / 1253
页数:6
相关论文
共 25 条
[1]   Long-Term Morbidity and Mortality Related to Falls in Hemodialysis Patients: Role of Age and Gender - A Pilot Study [J].
Abdel-Rahman, Emaad M. ;
Yan, Guofen ;
Turgut, Faruk ;
Balogun, Rasheed A. .
NEPHRON CLINICAL PRACTICE, 2011, 118 (03) :C278-C284
[2]   Increased risk of hip fracture among patients with end-stage renal disease [J].
Alem, AM ;
Sherrard, DJ ;
Gillen, DL ;
Weiss, NS ;
Beresford, SA ;
Heckbert, SR ;
Wong, C ;
Stehman-Breen, C .
KIDNEY INTERNATIONAL, 2000, 58 (01) :396-399
[3]   Reliability and concurrent validity of the Expanded Timed Up-and-Go test in older people with impaired mobility [J].
Botolfsen, Pernille ;
Helbostad, Jorunn L. ;
Moe-Nilssen, Rolf ;
Wall, James C. .
PHYSIOTHERAPY RESEARCH INTERNATIONAL, 2008, 13 (02) :94-106
[4]   Association between 25-hydroxyvitamin D, somatic muscle weakness and falls risk in end-stage renal failure [J].
Boudville, N. ;
Inderjeeth, C. ;
Elder, G. J. ;
Glendenning, P. .
CLINICAL ENDOCRINOLOGY, 2010, 73 (03) :299-304
[5]   RISK-FACTORS FOR FALLS IN A COMMUNITY-BASED PROSPECTIVE-STUDY OF PEOPLE 70 YEARS AND OLDER [J].
CAMPBELL, AJ ;
BORRIE, MJ ;
SPEARS, GF .
JOURNALS OF GERONTOLOGY, 1989, 44 (04) :M112-M117
[6]   Increased incidence of hip fractures in dialysis patients with low serum parathyroid hormone [J].
Coco, M ;
Rush, H .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2000, 36 (06) :1115-1121
[7]   Falls and fall-related injuries in older dialysis patients [J].
Cook, Wendy L. ;
Tomlinson, George ;
Donaldson, Meghan ;
Markowitz, Samuel N. ;
Naglie, Gary ;
Sobolev, Boris ;
Jassal, Sarbjit V. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 1 (06) :1197-1204
[8]   Prevalence of falls among seniors maintained on hemodialysis [J].
Cook, Wendy L. ;
Jassal, Sarbjit Vanita .
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2005, 37 (03) :649-652
[9]   The L test of functional mobility: Measurement properties of a modified version of the timed "Up & Go" test designed for people with lower-limb amputations [J].
Deathe, AB ;
Miller, WC .
PHYSICAL THERAPY, 2005, 85 (07) :626-635
[10]   Falls in hemodialysis patients: Prospective study of incidence, risk factors, and complications [J].
Desmet, C ;
Beguin, C ;
Swine, C ;
Jadoul, M .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2005, 45 (01) :148-153