Paediatric type 1 diabetes 2018: Clinical and research insights

被引:1
作者
Zborovski, Stephen J. [1 ]
Mahmud, Farid H. [1 ]
机构
[1] Univ Toronto, Dept Pediat, Hosp Sick Children, Div Endocrinol, Toronto, ON, Canada
关键词
Type; 1; diabetes; Paediatrics; Review; INSULIN-PUMP THERAPY; GLYCEMIC CONTROL; T1D EXCHANGE; CHILDREN; ADOLESCENTS; THICKNESS; MELLITUS; DEGLUDEC; PROTEIN; IMPACT;
D O I
10.1093/pch/pxx214
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The management of children and adolescents with type 1 diabetes continues to progress as clinical and technological innovations enter into practice. Variability in glucose readings can present a significant challenge for care providers, patients and families alike and recent research demonstrates that insulin selection and site-related lipohypertrophy can significantly influence blood glucose levels. New technology aims to improve both glycemic control and quality of life. New insulin analogues have been developed and insulin pumps and continuous glucose monitoring systems continue to evolve toward a fully closed-loop system. While such systems are not yet currently available, incremental features such as 'low glucose suspend' are offered. As well, glucose sensors are now available that can be used for insulin dosing while reducing the number of capillary blood sugar checks. This review aims to provide the clinician with an overview of some of these latest aspects of diabetes care for children and adolescents.
引用
收藏
页码:198 / 202
页数:5
相关论文
共 31 条
[11]   Continuous glucose monitoring systems for type 1 diabetes mellitus [J].
Langendam, Miranda W. ;
Luijf, Yoeri M. ;
Hooft, Lotty ;
DeVries, J. Hans ;
Mudde, Aart H. ;
Scholten, Rob J. P. M. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2012, (01)
[12]   Skin and subcutaneous thickness at injecting sites in children with diabetes: ultrasound findings and recommendations for giving injection [J].
Lo Presti, Donatella ;
Ingegnosi, Carmela ;
Strauss, Kenneth .
PEDIATRIC DIABETES, 2012, 13 (07) :525-533
[13]   Pharmacokinetics and Pharmacodynamics of NPH Insulin in Type 1 Diabetes: The Importance of Appropriate Resuspension Before Subcutaneous Injection [J].
Lucidi, Paola ;
Porcellati, Francesca ;
Andreoli, Anna Marinelli ;
Carriero, Ilaria ;
Candeloro, Paola ;
Cioli, Patrizia ;
Bolli, Geremia B. ;
Fanelli, Carmine G. .
DIABETES CARE, 2015, 38 (12) :2204-2210
[14]   Contrasting the clinical care and outcomes of 2,622 children with type 1 diabetes less than 6 years of age in the United States T1D Exchange and German/Austrian DPV registries [J].
Maahs, David M. ;
Hermann, Julia M. ;
DuBose, Stephanie N. ;
Miller, Kellee M. ;
Heidtmann, Bettina ;
DiMeglio, Linda A. ;
Rami-Merhar, Birgit ;
Beck, Roy W. ;
Schober, Edith ;
Tamborlane, William V. ;
Kapellen, Thomas M. ;
Holl, Reinhard W. .
DIABETOLOGIA, 2014, 57 (08) :1578-1585
[15]   ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes [J].
Marcovecchio, M. Loredana ;
Chiesa, Scott T. ;
Bond, Simon ;
Daneman, Denis ;
Dawson, Sarah ;
Donaghue, Kim C. ;
Jones, Timothy W. ;
Mahmud, Farid H. ;
Marshall, Sally M. ;
Neil, H. Andrew W. ;
Dalton, R. Neil ;
Deanfield, John ;
Dunger, David B. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (18) :1733-1745
[16]   Insulin analogues in type 1 diabetes mellitus: getting better all the time [J].
Mathieu, Chantal ;
Gillard, Pieter ;
Benhalima, Katrien .
NATURE REVIEWS ENDOCRINOLOGY, 2017, 13 (07) :385-399
[17]   Glycaemic control of Type1 diabetes in clinical practice early in the 21st century: an international comparison [J].
McKnight, J. A. ;
Wild, S. H. ;
Lamb, M. J. E. ;
Cooper, M. N. ;
Jones, T. W. ;
Davis, E. A. ;
Hofer, S. ;
Fritsch, M. ;
Schober, E. ;
Svensson, J. ;
Almdal, T. ;
Young, R. ;
Warner, J. T. ;
Delemer, B. ;
Souchon, P. F. ;
Holl, R. W. ;
Karges, W. ;
Kieninger, D. M. ;
Tigas, S. ;
Bargiota, A. ;
Sampanis, C. ;
Cherubini, V. ;
Gesuita, R. ;
Strele, I. ;
Pildava, S. ;
Coppell, K. J. ;
Magee, G. ;
Cooper, J. G. ;
Dinneen, S. F. ;
Eeg-Olofsson, K. ;
Svensson, A. -M. ;
Gudbjornsdottir, S. ;
Veeze, H. ;
Aanstoot, H. -J. ;
Khalangot, M. ;
Tamborlane, W. V. ;
Miller, K. M. .
DIABETIC MEDICINE, 2015, 32 (08) :1036-1050
[18]   The Efficacy and Safety of Insulin Degludec Given in Variable Once-Daily Dosing Intervals Compared With Insulin Glargine and Insulin Degludec Dosed at the Same Time Daily A 26-week, randomized, open-label, parallel-group, treat-to-target trial in individuals with type 2 diabetes [J].
Meneghini, Luigi ;
Atkin, Stephen L. ;
Gough, Stephen C. L. ;
Raz, Itamar ;
Blonde, Lawrence ;
Shestakova, Marina ;
Bain, Stephen ;
Johansen, Thue ;
Begtrup, Kamilla ;
Birkeland, Kare I. .
DIABETES CARE, 2013, 36 (04) :858-864
[19]   Current State of Type 1 Diabetes Treatment in the US: Updated Data From the T1D Exchange Clinic Registry [J].
Miller, Kellee M. ;
Foster, Nicole C. ;
Beck, Roy W. ;
Bergenstal, Richard M. ;
DuBose, Stephanie N. ;
DiMeglio, Linda A. ;
Maahs, David M. ;
Tamborlane, William V. .
DIABETES CARE, 2015, 38 (06) :971-978
[20]   Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus [J].
Misso, M. L. ;
Egberts, K. J. ;
Page, M. ;
O'Connor, D. ;
Shaw, J. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2010, (01)