Synthesis of silver nanoparticles from Phenerochaete chrysosporium (MTCC-787) and their antibacterial activity against human pathogenic bacteria

被引:233
作者
Saravanan, Muthupandian [1 ]
Arokiyaraj, Selvaraj [2 ]
Lakshmi, Thangavelu [3 ]
Pugazhendhi, Arivalagan [4 ]
机构
[1] Mekelle Univ, Coll Hlth Sci, Inst Biomed Sci, Dept Microbiol & Immunol, Mekele, Ethiopia
[2] SeJong Univ, Dept Food Sci & Biotechnol, Seoul, South Korea
[3] Saveetha Univ, Dept Pharmacol, Madras, Tamil Nadu, India
[4] Ton Duc Thang Univ, Fac Environm & Labour Safety, Innovat Green Prod Synth & Renewable Environm Dev, Ho Chi Minh City, Vietnam
关键词
Silver nanoparticles; Phenerochaete chrysosporium; Antibacterial activity; Human pathogen; GOLD NANOPARTICLES; EXTRACELLULAR SYNTHESIS; ANTIMICROBIAL EFFICACY; FUNGUS; EXTRACT; BIOSYNTHESIS; BIOREDUCTION; MALARIA;
D O I
10.1016/j.micpath.2018.02.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The present study elucidates an eco-friendly method for synthesizing silver nanoparticles using Phenerochaete chtysosporium (MTCC-787), its bactericidal and cytotoxic effect were studied. The formation of nanoparticles was evidenced by color change and UV-Vis spectroscopy. Atomic Force Microscope and Transmission electron microscope, showed spherical and oval shapes particles in the sizes ranging between 34 and 90 nm. The biosynthesised silver nanoparticles showed significant antibacterial activity against Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus and Staphylococcus epidermidis at a high dose. Further, the nano particles observed to be non-toxic at 12.5 mu g/ml towards fibroblast cells.
引用
收藏
页码:68 / 72
页数:5
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