Retroperitoneal sarcomas: Combined-modality treatment approaches

被引:100
作者
Raut, Chandrajit P.
Pisters, Peter W. T.
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Surg Oncol, Houston, TX 77030 USA
[2] Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA
[3] Dana Farber Canc Inst, Boston, MA 02115 USA
关键词
retroperitoneal sarcoma; soft tissue sarcoma; external beam radiation; intraoperative radiation; chemoradiation;
D O I
10.1002/jso.20543
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Retroperitoneal sarcomas (RPS) are rare tumors, accounting for approximately 15% of soft tissue sarcomas. Surgical resection of localized tumors with gross and microscopically negative margins remains the standard of care. However, because RPS are frequently large and locally advanced, resections are often incomplete, resulting in local recurrence. Investigators are evaluating combined-modality therapies to improve local control and disease-specific survival. This review outlines current concepts and evolving treatment strategies in the diagnosis, staging, and management of RPS.
引用
收藏
页码:81 / 87
页数:7
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