Evolution of protein structures and functions

被引：126
作者：
Kinch, LN
Grishin, NV
机构：
[1] Univ Texas, SW Med Ctr, Howard Hughes Med Inst, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2002年 / 12卷 / 03期
关键词：
D O I：
10.1016/S0959-440X(02)00338-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Within the ever-expanding repertoire of known protein sequences and structures, many examples of evolving three-dimensional structures are emerging that illustrate the plasticity and robustness of protein folds. The mechanisms by which protein folds change often include the fusion of duplicated domains, followed by divergence through mutation. Such changes reflect both the stability of protein folds and the requirements of protein function.
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页码：400 / 408
页数：9
相关论文
共 47 条
[11]  
Cordes MHJ, 2000, NAT STRUCT BIOL, V7, P1129
[12]   Evolution of a protein fold in vitro [J].
Cordes, MHJ ;
Walsh, NP ;
McKnight, CJ ;
Sauer, RT .
SCIENCE, 1999, 284 (5412) :325-327
[13]   CRYSTAL-STRUCTURE OF VIBRIO-CHOLERAE NEURAMINIDASE REVEALS DUAL LECTIN-LIKE DOMAINS IN ADDITION TO THE CATALYTIC DOMAIN [J].
CRENNELL, S ;
GARMAN, E ;
LAVER, G ;
VIMR, E ;
TAYLOR, G .
STRUCTURE, 1994, 2 (06) :535-544
[14]   Peptide exosite inhibitors of factor VIIa as anticoagulants [J].
Dennis, MS ;
Eigenbrot, C ;
Skelton, NJ ;
Ultsch, MH ;
Santell, L ;
Dwyer, MA ;
O'Connell, MP ;
Lazarus, RA .
NATURE, 2000, 404 (6777) :465-470
[15]   Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-Å resolution [J].
Du, XL ;
Choi, IG ;
Kim, R ;
Wang, WR ;
Jancarik, J ;
Yokota, H ;
Kim, SH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) :14079-14084
[16]   STRUCTURE OF THE COMPLEX OF YEAST ADENYLATE KINASE WITH THE INHIBITOR P1,P5-DI(ADENOSINE-5'-)PENTAPHOSPHATE AT 2.6 A RESOLUTION [J].
EGNER, U ;
TOMASSELLI, AG ;
SCHULZ, GE .
JOURNAL OF MOLECULAR BIOLOGY, 1987, 195 (03) :649-658
[17]   The factor VII zymogen structure reveals reregistration of β strands during activation [J].
Eigenbrot, C ;
Kirchhofer, D ;
Dennis, MS ;
Santell, L ;
Lazarus, RA ;
Stamos, J ;
Ultsch, MH .
STRUCTURE, 2001, 9 (07) :627-636
[18]   The β-slip:: A novel concept in transthyretin amyloidosis [J].
Eneqvist, T ;
Andersson, K ;
Olofsson, A ;
Lundgren, E ;
Sauer-Eriksson, AE .
MOLECULAR CELL, 2000, 6 (05) :1207-1218
[19]  
Fetrow J S, 1998, Pac Symp Biocomput, P485
[20]   X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain [J].
Fieulaine, S ;
Morera, S ;
Poncet, S ;
Monedero, V ;
Gueguen-Chaignon, V ;
Galinier, A ;
Janin, J ;
Deutscher, J ;
Nessler, S .
EMBO JOURNAL, 2001, 20 (15) :3917-3927
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