Safety Assessment of Dimethicone Crosspolymers as Used in Cosmetics

被引：11
作者：
Becker, Lillian C. [1 ]
Bergfeld, Wilma F.
Belsito, Donald V.
Hill, Ronald A.
Klaassen, Curtis D.
Liebler, Daniel C.
Marks, James G., Jr.
Shank, Ronald C.
Slaga, Thomas J.
Snyder, Paul W.
Andersen, F. Alan [1 ]
机构：
[1] Cosmet Ingredient Rev, Washington, DC USA
来源：
INTERNATIONAL JOURNAL OF TOXICOLOGY | 2014年 / 33卷
关键词：
cosmetics; safety; dimethicone crosspolymers;
D O I：
10.1177/1091581814524963
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of 62 dimethicone crosspolymer ingredients as used in cosmetics. These ingredients function mostly as absorbents, bulking agents, film formers, hair-conditioning agents, emollient skin-conditioning agents, slip modifiers, surface modifiers, and nonaqueous viscosity-increasing agents. The Panel reviewed available animal and human data related to these polymers and addressed the issue of residual monomers. The Panel concluded that these dimethicone crosspolymer ingredients are safe in the practices of use and concentration as given in this safety assessment.
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收藏
页码：65S / 115S
页数：51
相关论文
共 31 条
[21]  
Rothe H :., 2011, Special aspects of cosmetic spray evaluation
[22]  
Shin-Etsu, 2010, SHIN ETS SIL S UNPUB
[23]  
Shin-Etsu, 2012, SUMM SAF STUD UNPUB
[24]  
Silicones Environmental Health and Safety Council, 20111000063817 SIL E
[25]  
Siltech Corporation, 2012, SILT INN SIL SPEC
[26]  
Starch MS, 2003, J COSMET SCI, V54, P193
[27]  
U.S. Food and Drug Administration. FDA database, 2010, COSM PROD FORM FREQ
[28]  
U.S. Food and Drug Administration. FDA Database, 2012, COSM PROD FORM UNPUB
[29]  
Wacker Chemie AG, 2010, PROD DOSS WACK BELS
[30]  
Wacker Chemie AG, 2011, PROD DOSS BELS P101
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