Asymmetric hydrogenation reactions with Rh and Ru complexes bearing phosphine-phosphites with an oxymethylene backbone

被引：7

作者：

Kleman, Patryk

Vaquero, Monica

Arribas, Inmaculada

Suarez, Andres

Alvarez, Eleuterio

Pizzano, Antonio ^{[1
]}

机构：

[1] CSIC, Inst Invest Quim, Seville 41092, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2014年 / 25卷 / 09期

关键词：

HIGHLY ENANTIOSELECTIVE HYDROFORMYLATION; P-OP LIGANDS; CU-CATALYZED 1,4-ADDITION; ALTERNATING COPOLYMERIZATION; IRIDIUM COMPLEXES; GRIGNARD-REAGENTS; OLEFINS; LIBRARY; HYDROCYANATION; PHOSPHONATES;

D O I：

10.1016/j.tetasy.2014.04.001

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Phosphine-phosphites 3a and 3b, derived from diphenylhydroxymethyl phosphine have been prepared. From these ligands [Rh(COD)(3a)]BF4 5a and RuCl2(3b)[(S,S)-DPEN] 6b (DPEN = 1,2-diphenylethylenediamine) were synthesized and their structure determined by X-ray diffraction. Ligands 3 are characterized by a small bite angle of 83 degrees. In addition, 5a led to an active catalyst for the hydrogenation of olefins, giving enantioselectivities of up to 96% ee. Likewise, compound 6b showed good activity and enantioselectivity in the hydrogenation of N-1-phenyl ethylidene aniline and a completed reaction at S/C = 500 in 24 h with 83% ee. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：744 / 749

页数：6