Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine Case report

被引:21
作者
Pirola, Elena [1 ]
Vergani, Francesco [1 ]
Casiraghi, Paolo [1 ]
Leone, Eugenio Biagio [2 ]
Guerra, Paolo [1 ]
Sganzerla, Erik Pietro [1 ]
机构
[1] Univ Milano Bicocca, Dept Neurosurg, Monza, Italy
[2] Univ Milano Bicocca, Dept Pathol, Monza, Italy
关键词
fibroblast growth factor; oncogenic osteomalacia; paraneoplastic syndrome; phosphaturic mesenchymal tumor; HYPOPHOSPHATEMIC OSTEOMALACIA; DIAGNOSIS; REMOVAL;
D O I
10.3171/2009.1.SPINE08351
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom wits diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail. (DOI: 10.3171/2009.1.SPINE08351)
引用
收藏
页码:329 / 333
页数:5
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