Generic Ledipasvir-Sofosbuvir Treatment for Adolescents With Chronic Hepatitis C Virus Infection

被引：10
作者：
Fouad, Hanan M. [1 ,2 ,7 ]
Sabry, Magda A. [2 ]
Ahmed, Amal [3 ]
Hassany, Mohamed [4 ]
Al Soda, Mohamed F. [5 ]
Aziz, Hossam Abdel [6 ]
机构：
[1] Helwan Univ, Fac Med, Dept Pediat, Cairo, Egypt
[2] Natl Hepatol & Trop Med Res Inst, Dept Pediat, Cairo, Egypt
[3] Natl Hepatol & Trop Med Res Inst, Dept Biochem & Mol Biol, Cairo, Egypt
[4] Natl Hepatol & Trop Med Res Inst, Dept Hepatol, Cairo, Egypt
[5] Ahmed Maher Teaching Hosp, Pediat & Neonatol Dept, Cairo, Egypt
[6] Ain Shams Univ, Hepatol Dept, Cairo, Egypt
[7] Helwan Univ, Fac Med, Pediat Dept, Cairo, Egypt
来源：
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2020年 / 9卷 / 03期
关键词：
adolescents; brand; Egypt; generic ledipasvir-sofosbuvir; HCV;
D O I：
10.1093/jpids/piz041
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We assessed the safety and efficacy of a generic form of ledipasvir-sofosbuvir for the treatment of hepatitis C virus infection in Egyptian adolescents and compared the results with those of treatment with the brand-named form. The generic form resulted in a high response rate, significant improvement in liver function, and mild adverse effects. These results are comparable with those of the brand form at a reduced price.
引用
收藏
页码：386 / 389
页数：4
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