Patient's comfort with and tolerability of thyroid core needle biopsy

被引:54
作者
Nasrollah, Naim [1 ]
Trimboli, Pierpaolo [2 ]
Rossi, Fabio [2 ]
Amendola, Stefano [2 ]
Guidobaldi, Leo [3 ]
Ventura, Claudio [2 ]
Maglio, Riccardo [4 ]
Nigri, Giuseppe [4 ]
Romanelli, Francesco [5 ]
Valabrega, Stefano [4 ]
Crescenzi, Anna [3 ]
机构
[1] Osped Israelit, Sect Surg, Rome, Italy
[2] Osped Israelit Roma, Sect Endocrinol & Diabetol, I-00148 Rome, Italy
[3] Osped Israelit, Sect Pathol, Rome, Italy
[4] Univ Roma La Sapienza, Dept Surg & Med Sci, I-00185 Rome, Italy
[5] Univ Roma La Sapienza, Dept Expt Med, I-00185 Rome, Italy
关键词
Thyroid; Core needle biopsy (CNB); Fine-needle aspiration (FNA); Comfort; Tolerability; ASPIRATION BIOPSY; NODULES; COMPLICATIONS;
D O I
10.1007/s12020-013-9979-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Recently, the core needle biopsy (CNB) has been proposed as a complementary test for thyroid nodules with inconclusive cytology by fine-needle aspiration (FNA). However, there have been no reports regarding patient comfort during and after CNB or tolerability of this procedure. Here we aimed to investigate and compare comfort with and tolerability of the CNB and FNA procedures. A 21 gauge needle was used for collection in CNB procedures, and a 23 gauge needle was used for collection in FNA procedures. Sixty-one consecutive patients underwent both biopsies and were asked to evaluate their comfort during and after these procedures by a structured questionnaire. A total of 58 (95 %) patients reported local pain during both biopsies. Two patients reported pain only during CNB, and one reported no pain. Mild pain was reported in 87 % of CNB cases. Local pain after biopsy was reported in 29 % of FNA and 45 % of CNB. The occurrence of pain in the first minutes following CNB was significantly higher than FNA (p = 0.008), while there was not a significant difference in pain at later time points after the procedures. Finally, patients were asked to evaluate the degree of tolerability of the two sampling techniques, and FNA and CNB were reported as tolerable in 82 and 83 %, respectively. The results from a questionnaire evaluating patients' comfort level showed no significant difference between the tolerability of CNB and FNA. This finding suggests that CNB may be performed with a reasonable level of patient comfort.
引用
收藏
页码:79 / 83
页数:5
相关论文
共 24 条
[11]   Comparison of sample adequacy, pain-scale ratings, and complications associated with ultrasound-guided fine-needle aspiration of thyroid nodules between two radiologists with different levels of experience [J].
Lee, Yoo Jin ;
Kim, Dong Wook ;
Jung, Soo Jin .
ENDOCRINE, 2013, 44 (03) :696-701
[12]   Bilateral intrathyroidal hemorrhage after fine needle aspiration completely resolved by compression without thyroidectomy [J].
Lee, Young Sun ;
Baek, Hong Sun ;
Park, Tae Sun ;
Jin, Heung Yong .
ENDOCRINE, 2013, 43 (02) :460-461
[13]  
LIU Q, 1995, AM SURGEON, V61, P628
[14]   Core-Needle Biopsy Is More Useful Than Repeat Fine-Needle Aspiration in Thyroid Nodules Read as Nondiagnostic or Atypia of Undetermined Significance by the Bethesda System for Reporting Thyroid Cytopathology [J].
Na, Dong Gyu ;
Kim, Ji-hoon ;
Sung, Jin Yong ;
Baek, Jung Hwan ;
Jung, Kyeong Cheon ;
Lee, Hunkyung ;
Yoo, Hyunju .
THYROID, 2012, 22 (05) :468-475
[15]   Thin core biopsy should help to discriminate thyroid nodules cytologically classified as indeterminate. A new sampling technique [J].
Nasrollah, Naim ;
Trimboli, Pierpaolo ;
Guidobaldi, Leo ;
Modica, Davide Domenico Cicciarella ;
Ventura, Claudio ;
Ramacciato, Giovanni ;
Taccogna, Silvia ;
Romanelli, Francesco ;
Valabrega, Stefano ;
Crescenzi, Anna .
ENDOCRINE, 2013, 43 (03) :659-665
[16]   ROLE OF CORE NEEDLE BIOPSY AND ULTRASONOGRAPHIC FINDING IN MANAGEMENT OF INDETERMINATE THYROID NODULES [J].
Park, Kyung Tae ;
Ahn, Soon-Hyun ;
Mo, Ji-Hun ;
Park, Young Joo ;
Park, Do Joong ;
Choi, Sang Il ;
Park, So-Yeon .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2011, 33 (02) :160-165
[17]   Systematic Review of Cases Reporting Blood Extravasation-Related Complications after Thyroid Fine-Needle Biopsy [J].
Polyzos, Stergios A. ;
Anastasilakis, Athanasios D. .
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2010, 39 (05) :532-541
[18]   Clinical complications following thyroid fine-needle biopsy: a systematic review [J].
Polyzos, Stergios A. ;
Anastasilakis, Athanasios D. .
CLINICAL ENDOCRINOLOGY, 2009, 71 (02) :157-165
[19]   Ultrasound-Guided Percutaneous Thyroid Nodule Core Biopsy: Clinical Utility in Patients with Prior Nondiagnostic Fine-Needle Aspirate [J].
Samir, Anthony E. ;
Vij, Abhinav ;
Seale, Melanie K. ;
Desai, Gaurav ;
Halpern, Elkan ;
Faquin, William C. ;
Parangi, Sareh ;
Hahn, Peter F. ;
Daniels, Gilbert H. .
THYROID, 2012, 22 (05) :461-467
[20]   Diagnostic accuracy of fine-needle aspiration versus core-needle biopsy for the diagnosis of thyroid malignancy in a clinical cohort [J].
Sung, Jin Yong ;
Na, Dong Gyu ;
Kim, Kyu Sun ;
Yoo, Hyunju ;
Lee, Hunkyung ;
Kim, Ji-hoon ;
Baek, Jung Hwan .
EUROPEAN RADIOLOGY, 2012, 22 (07) :1564-1572