Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

被引：17

作者：

Shimpo, K ^{[1
]}

Ida, C ^{[1
]}

Chihara, T ^{[1
]}

Beppu, H ^{[1
]}

Kaneko, T ^{[1
]}

Kuzuya, H ^{[1
]}

机构：

[1] Fujita Hlth Univ, Fujita Mem Inst Pharmacognosy, Hisai, Mie 5141296, Japan

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷 / 05期

关键词：

Aloe orborescens Miller var. natalensis Berger (Aloe arborescens); 12-O-tetradecanoylphorbol-13-acetate (TPA); ear oedema; putrescine increase; anti-tumour promotion;

D O I：

10.1002/ptr.938

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chernopreventive agents against tumour promotion. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：491 / 493

页数：3