Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin

被引：17

作者：

Shimpo, K ^{[1
]}

Ida, C ^{[1
]}

Chihara, T ^{[1
]}

Beppu, H ^{[1
]}

Kaneko, T ^{[1
]}

Kuzuya, H ^{[1
]}

机构：

[1] Fujita Hlth Univ, Fujita Mem Inst Pharmacognosy, Hisai, Mie 5141296, Japan

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷 / 05期

关键词：

Aloe orborescens Miller var. natalensis Berger (Aloe arborescens); 12-O-tetradecanoylphorbol-13-acetate (TPA); ear oedema; putrescine increase; anti-tumour promotion;

D O I：

10.1002/ptr.938

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chernopreventive agents against tumour promotion. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：491 / 493

页数：3

共 13 条

[1]

Fahim FA, 1997, J TUMOR MARKER ONCOL, V12, P127

[2]

Fahim FA, 1993, J TUMOR MARKER ONCOL, V8, P27

[3]

FUJITA K, 1993, PARM THERAPEUTIC EFF

[4]

FUJITA K, 1994, PHARM EFFECTS KIDACH

[5]

*JPN HLTH FOOD NUT, 1997, PUBL NOT HLTH FOOD S, P86

[6] Determination of aloenin, barbaloin and isobarbaloin in Aloe species by micellar electrokinetic chromatography [J].

Kuzuya, H ;

Tamai, I ;

Beppu, H ;

Shimpo, K ;

Chihara, T .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2001, 752 (01) :91-97

[7]

OBRIEN TG, 1980, POLYAMINES BIOMEDICA, P237

[8]

SHIMPO K, 1998, FUJITA GAKUEN IGAKKA, V22, P157

[9] FRACTIONATION OF MOUSE EPIDERMAL CHROMATIN COMPONENTS [J].

SLAGA, TJ ;

DAS, SB ;

RICE, JM ;

THOMPSON, S .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1974, 63 (04) :343-349

[10] QUANTITATION OF POLYAMINES IN CULTURED-CELLS AND TISSUE-HOMOGENATES BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF THEIR BENZOYL DERIVATIVES [J].

VERKOELEN, CF ;

ROMIJN, JC ;

SCHROEDER, FH ;

VANSCHALKWIJK, WP ;

SPLINTER, TAW .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 426 (01) :41-54

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