MAGNETIC RESONANCE IMAGING PHENOTYPING OF BECKER MUSCULAR DYSTROPHY

被引：28

作者：

Faridian-Aragh, Neda ^{[1
]}

Wagner, Kathryn R. ^{[2
,3
,4
]}

Leung, Doris G. ^{[2
]}

Carrino, John A. ^{[1
]}

机构：

[1] Johns Hopkins Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

[2] Kennedy Krieger Inst, Ctr Genet Muscle Disorders, Baltimore, MD USA

[3] Johns Hopkins Sch Med, Dept Neurol & Neurosci, Baltimore, MD 21287 USA

[4] Johns Hopkins Sch Med, Dept Neurosci, Baltimore, MD 21287 USA

来源：

MUSCLE & NERVE | 2014年 / 50卷 / 06期

关键词：

Becker muscular dystrophy; upper extremity; lower extremity; fatty infiltration; muscular dystrophy; MRI; phenotype; MUSCLE INVOLVEMENT; MRI; MYOPATHIES; PATTERNS; DISEASES;

D O I：

10.1002/mus.24246

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: There is little information on magnetic resonance imaging (MRI) phenotypes of Becker muscular dystrophy (BMD). This study presents the MRI phenotyping of the upper and lower extremities of a large cohort of BMD patients. Methods: In this retrospective study, MRI images of 33 BMD subjects were evaluated for severity, distribution, and symmetry of involvement. Results: Teres major, triceps long head, biceps brachii long head, gluteus maximus, gluteus medius, vasti, adductor longus, adductor magnus, semitendinosus, semimembranosus, and biceps femoris muscles showed the highest severity and frequency of involvement. All analyzed muscles had a high frequency of symmetric involvement. There was significant variability of involvement between muscles within some muscle groups, most notably the arm abductors, posterior arm muscles, medial thigh muscles, and lateral hip rotators. Conclusions: This study showed a distinctive pattern of involvement of extremity muscles in BMD subjects. Muscle Nerve 50: 962-967, 2014

引用

页码：962 / 967

页数：6

共 15 条

[1] T2 mapping provides multiple approaches for the characterization of muscle involvement in neuromuscular diseases: a cross-sectional study of lower leg muscles in 5-15-year-old boys with Duchenne muscular dystrophy [J].

Arpan, Ishu ;

Forbes, Sean C. ;

Lott, Donovan J. ;

Senesac, Claudia R. ;

Daniels, Michael J. ;

Triplett, William T. ;

Deol, Jasjit K. ;

Sweeney, H. Lee ;

Walter, Glenn A. ;

Vandenborne, Krista .

NMR IN BIOMEDICINE, 2013, 26 (03) :320-328

[2]

desVisser M, 1985, MUSCLE NERVE, V8, P435

[3] Distinct muscle imaging patterns in myofibrillar myopathies [J].

Fischer, D. ;

Kley, R. A. ;

Strach, K. ;

Meyer, C. ;

Sommer, T. ;

Eger, K. ;

Rolfs, A. ;

Meyer, W. ;

Pou, A. ;

Pradas, J. ;

Heyer, C. M. ;

Grossmann, A. ;

Huebner, A. ;

Kress, W. ;

Reimann, J. ;

Schroeder, R. ;

Eymard, B. ;

Fardeau, M. ;

Udd, B. ;

Goldfarb, L. ;

Vorgerd, M. ;

Olive, M. .

NEUROLOGY, 2008, 71 (10) :758-765

[4] Diagnostic value of muscle MRI in differentiating LGMD2I from other LGMDs [J].

Fischer, D ;

Walter, MC ;

Kesper, K ;

Petersen, JA ;

Aurino, S ;

Nigro, V ;

Kubisch, C ;

Meindl, T ;

Lochmüller, H ;

Wilhelm, K ;

Urbach, H ;

Schröder, R .

JOURNAL OF NEUROLOGY, 2005, 252 (05) :538-547

[5] Magnetic resonance imaging of muscle in congenital myopathies associated with RYR1 mutations [J].

Jungbluth, H ;

Davis, MR ;

Müller, C ;

Counsell, S ;

Allsop, J ;

Chattopadhyay, A ;

Messina, S ;

Mercuri, E ;

Laing, NG ;

Sewry, CA ;

Bydder, G ;

Muntoni, F .

NEUROMUSCULAR DISORDERS, 2004, 14 (12) :785-790

[6] MAGNETIC-RESONANCE-IMAGING OF PRIMARY SKELETAL-MUSCLE DISEASES - PATTERNS OF DISTRIBUTION AND SEVERITY OF INVOLVEMENT [J].

LAMMINEN, AE .

BRITISH JOURNAL OF RADIOLOGY, 1990, 63 (756) :946-950

[7] DUCHENNE MUSCULAR-DYSTROPHY - MR GRADING SYSTEM WITH FUNCTIONAL CORRELATION [J].

LIU, GC ;

JONG, YJ ;

CHIANG, CH ;

JAW, TS .

RADIOLOGY, 1993, 186 (02) :475-480

[8] Muscle MRI in Ullrich congenital muscular dystrophy and Bethlem myopathy [J].

Mercuri, E ;

Lampe, A ;

Allsop, J ;

Knight, R ;

Pane, M ;

Kinali, M ;

Bonnemann, C ;

Flanigan, K ;

Lapini, A ;

Bushby, K ;

Pepe, G ;

Muntoni, F .

NEUROMUSCULAR DISORDERS, 2005, 15 (04) :303-310

[9] Clinical and imaging findings in six cases of congenital muscular dystrophy with rigid spine syndrome linked to chromosome 1p (RSMD1) [J].

Mercuri, E ;

Talim, B ;

Moghadaszadeh, B ;

Petit, N ;

Brockington, M ;

Counsell, S ;

Guicheney, P ;

Muntoni, F ;

Merlini, L .

NEUROMUSCULAR DISORDERS, 2002, 12 (7-8) :631-638

[10] Selective muscle involvement on magnetic resonance imaging in autosomal dominant Emery-Dreifuss muscular dystrophy [J].

Mercuri, E ;

Counsell, S ;

Allsop, J ;

Jungbluth, H ;

Kinali, M ;

Bonne, G ;

Schwartz, K ;

Bydder, G ;

Dubowitz, V ;

Muntoni, F .

NEUROPEDIATRICS, 2002, 33 (01) :10-14

← 1 2 →