Colorectal Liver Metastasis: Overview of Treatment Paradigm Highlighting the Role of Ablation

被引:20
作者
Venkat, Shree R. [1 ]
Mohan, Prasoon P. [1 ]
Gandhi, Ripal T. [2 ]
机构
[1] Univ Miami, Miller Sch Med, 1475 NW 12th Ave,Ste C080, Miami, FL 33136 USA
[2] Miami Cardiac & Vasc Inst, Miami, FL USA
关键词
colorectal cancer; liver metastases; radiofrequency ablation; DRUG-ELUTING BEADS; RADIOFREQUENCY-ABLATION; MICROWAVE ABLATION; ANTIBIOTIC-PROPHYLAXIS; HEPATIC METASTASES; IRREVERSIBLE ELECTROPORATION; HEPATOCELLULAR-CARCINOMA; PROGNOSTIC-FACTORS; RADIATION-THERAPY; PHASE-II;
D O I
10.2214/AJR.17.18574
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
OBJECTIVE. The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation. CONCLUSION. A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.
引用
收藏
页码:883 / 890
页数:8
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