Sinus Node Dysfunction in Association With Chronic Lithium Therapy: A Case Report and Review of Literature

被引：23

作者：

Talati, Sapan N. ^{[1
]}

Aslam, Ahmad E. ^{[1
]}

Vasavada, Balendu ^{[1
]}

机构：

[1] Long Isl Coll Hosp, Div Internal Med & Cardiovasc Dis, Brooklyn, NY 11201 USA

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2009年 / 16卷 / 03期

关键词：

sinus node dysfunction; chronic lithium use; cardiovascular effects; ABNORMALITIES;

D O I：

10.1097/MJT.0b013e3181822564

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Lithium is derived from the Greek word "lithia" which means "stone." Since its discovery by the Swedish chemist Arfedsson in the year 1817, it has been used for treatment of gout, hypertension, uremia, and rheumatism. Currently, lithium is the treatment of choice for the long-term control of mania and to prevent relapse in bipolar disorder. It has a narrow therapeutic :index (0.6-1.2 mEq/L). Lithium overdose has been associated with a wide range of cardiovascular complications including cardiac arrhythmias and interstitial myocarditis. We present a review of published cases relevant to lithium-related cardiotoxicity.

引用

页码：274 / 278

页数：5

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