Sclerouveitis Associated with Rosai-Dorfman Disease in an HIV-infected Patient

被引:12
|
作者
Monroe, Anne K. [1 ]
Burkholder, Bryn M. [2 ]
Butler, Nicholas J. [2 ]
Duffield, Amy S. [3 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Med, Div Gen Internal Med, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Sch Med, Dept Ophthalmol, Div Ocular Immunol, Baltimore, MD 21205 USA
[3] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA
关键词
Corticosteroids; emperipolesis; HIV; Rosai-Dorfman; sclerouveitis; SINUS HISTIOCYTOSIS; MASSIVE LYMPHADENOPATHY; INVOLVEMENT;
D O I
10.3109/09273948.2013.767914
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.
引用
收藏
页码:236 / 238
页数:3
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