The Escherichia coli K5 Capsule Is Not Synthesized in a Protected Compartment within the Cytoplasm

被引:5
作者
Hudson, Thomas [1 ]
Goldrick, Marie [1 ]
Roberts, Ian S. [1 ]
机构
[1] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England
基金
英国生物技术与生命科学研究理事会;
关键词
GENE-CLUSTER; BIOSYNTHESIS; POLYSACCHARIDE; EXPRESSION; COMPLEX; GLYCOSYLTRANSFERASE; IDENTIFICATION; ANTIGEN; KFIA;
D O I
10.1128/JB.01371-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The intracellular expression of the K5 lyase enzyme, which degrades the K5 polysaccharide, decreased cell surface expression of the Escherichia coli K5 capsule. This indicates that biosynthesis of K5 polysaccharide in the cytoplasm is accessible to the action of K5 lyase and is not synthesized within a protected cytoplasmic compartment.
引用
收藏
页码:1716 / 1718
页数:3
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